Mavilia-Scranton Marianna G, Wu George Y, Dharan Murali
Department of Medicine, Division of Gastroenterology and Hepatology, University of Connecticut, Farmington CT, USA.
J Clin Transl Hepatol. 2023 Jun 28;11(3):670-674. doi: 10.14218/JCTH.2022.00362. Epub 2023 Jan 19.
() infection is widely prevalent worldwide. infection has been reported to be a risk factor for the development of insulin resistance, nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), liver fibrosis, and cirrhosis. Because treatment for NAFLD, other than weight loss is limited, the treatment for infection is well established. It is important to determine whether screening and treatment for H. pylori infection should be considered in patients with no gastrointestinal symptoms. The aim of this mini-review is to evaluate the association between infection and NAFLD including epidemiology, pathogenesis, and the evidence for infection as a modifiable risk factor for preventing or treating NAFLD.
(某种感染)在全球广泛流行。据报道,该感染是胰岛素抵抗、非酒精性脂肪性肝病(NAFLD)、非酒精性脂肪性肝炎(NASH)、肝纤维化和肝硬化发生的危险因素。由于除了减重之外,NAFLD的治疗方法有限,而该感染的治疗方法已很成熟。确定无症状胃肠道疾病患者是否应考虑进行幽门螺杆菌感染筛查和治疗很重要。本综述的目的是评估该感染与NAFLD之间的关联,包括流行病学、发病机制以及该感染作为预防或治疗NAFLD的可改变危险因素的证据。