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用于设计溶剂回收工艺的交互式软件工具的开发

Development of an Interactive Software Tool for Designing Solvent Recovery Processes.

作者信息

Stengel Jake P, Lehr Austin L, Aboagye Emmanuel A, Chea John D, Yenkie Kirti M

机构信息

Department of Chemical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey08028, United States.

出版信息

Ind Eng Chem Res. 2023 Jan 20;62(5):2090-2103. doi: 10.1021/acs.iecr.2c02920. eCollection 2023 Feb 8.

DOI:10.1021/acs.iecr.2c02920
PMID:36972192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10035026/
Abstract

Solvents are used in chemical and pharmaceutical industries as a reaction medium, selective dissolution and extraction media, and dilution agents. Thus, a sizable amount of solvent waste is generated due to process inefficiencies. Most common ways of handling solvent waste are on-site, off-site disposal, and incineration, which have a considerable negative environmental impact. Solvent recovery is typically not used because of potential difficulties in achieving required purity guidelines, as well as additional infrastructure and investments that are needed. To this end, this problem must be studied carefully by involving aspects from capital needs, environmental benefits, and comparison with traditional disposal methods, while achieving the required purity. Thus, we have developed a user-friendly software tool that allows engineers to easily access solvent recovery options and predict an economical and environmentally favorable strategy, given a solvent-containing waste stream. This consists of a maximal process flow diagram that encompasses multiple stages of separations and technologies within those stages. This process flow diagram develops the superstructure that provides multiple technology pathway options for any solvent waste stream. Separation technologies are placed in different stages; depending on the component, they can separate in terms of their physical and chemical properties. A comprehensive chemical database is created to store all relevant chemical and physical properties. The pathway prediction is modeled as an economic optimization problem in General Algebraic Modeling Systems (GAMS). With GAMS code as the backend, a Graphical User Interface (GUI) is created in Matlab App Designer to provide a user-friendly tool to the chemical industry. This tool can act as a guidance system to assist professional engineers and provide an easy comparative estimate in the early stages of process design.

摘要

溶剂在化学和制药行业中用作反应介质、选择性溶解和萃取介质以及稀释剂。因此，由于工艺效率低下会产生大量的溶剂废物。处理溶剂废物最常见的方法是现场处理、场外处置和焚烧，这些方法对环境有相当大的负面影响。由于难以达到所需的纯度标准，以及需要额外的基础设施和投资，通常不采用溶剂回收。为此，必须从资本需求、环境效益以及与传统处置方法的比较等方面进行仔细研究，同时要达到所需的纯度。因此，我们开发了一个用户友好的软件工具，使工程师能够轻松获取溶剂回收选项，并在给定含溶剂废物流的情况下预测经济且环境友好的策略。这包括一个最大工艺流程示意图，涵盖了多个分离阶段以及这些阶段内的技术。该工艺流程示意图构建了上层结构，为任何溶剂废物流提供了多种技术路径选项。分离技术置于不同阶段；根据组分的不同，它们可以依据物理和化学性质进行分离。创建了一个综合化学数据库来存储所有相关的化学和物理性质。路径预测在通用代数建模系统（GAMS）中被建模为一个经济优化问题。以GAMS代码作为后端，在Matlab App Designer中创建了一个图形用户界面（GUI），为化学工业提供一个用户友好的工具。这个工具可以作为一个指导系统，协助专业工程师，并在工艺设计的早期阶段提供简单的比较估计。

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本文引用的文献

1
Synthesis and analysis of separation networks for the recovery of intracellular chemicals generated from microbial-based conversions.用于回收基于微生物转化产生的细胞内化学物质的分离网络的合成与分析。
Biotechnol Biofuels. 2017 May 8;10:119. doi: 10.1186/s13068-017-0804-2. eCollection 2017.
2
A roadmap for the synthesis of separation networks for the recovery of bio-based chemicals: Matching biological and process feasibility.生物基化学品回收用分离网络合成路线图：生物学可行性与过程可行性相匹配。
Biotechnol Adv. 2016 Dec;34(8):1362-1383. doi: 10.1016/j.biotechadv.2016.10.003. Epub 2016 Oct 15.
3
Sustainable development of process facilities: state-of-the-art review of pollution prevention frameworks.
工艺设施的可持续发展：污染预防框架的最新综述
J Hazard Mater. 2008 Jan 15;150(1):4-20. doi: 10.1016/j.jhazmat.2007.08.062. Epub 2007 Aug 30.
4
Thermal and catalytic incinerators for the control of VOCs.用于控制挥发性有机化合物的热力和催化焚烧炉。
J Air Waste Manage Assoc. 1991 Jan;41(1):92-8. doi: 10.1080/10473289.1991.10466828.
5
Air emissions from the incineration of hazardous waste.危险废物焚烧产生的空气排放物。
Toxicol Ind Health. 1990 Oct;6(5):23-51.