Koyuncuer Ali, Zen Tulay
University of Health Sciences Turkey, Umraniye Training and Research Hospital, Clinic of Pathology, Istanbul, Turkey.
Istanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Clinic of Pathology, Istanbul, Turkey.
Medeni Med J. 2023 Mar 28;38(1):39-44. doi: 10.4274/MMJ.galenos.2023.22755.
We aimed to evaluate of colorectal high-risk polyps and synchronized neoplasms and carcinomas with anatomical localization and demographic characteristics.
Between July 1, 2018 and July 1, 2022, 1137 polypectomy materials of 678 consecutive patients who were diagnosed in the pathology department and underwent total colonoscopy were included in the study. All epithelial polyps were re-classified according to the World Health Organization classification of digestive system tumors-2019, 5 edition.
The cases of 60.5% were male and 39.5% were female. The mean age of patients with polyps was 61.1 (±11.1) years. There was a statistically significant difference between the presence of gender and all epithelial polyps (p=0.044). Epithelial polyps were more common in men than in women (ratio; male/female 1.58:1). While the average size of the polyps was 5.2 (±5.08) millimeters (mm), 86.6% of all polyps were smaller than 10 mm. Solitary polyps were observed in 62.5% of all polyps, and multiple polyps were observed in 37.5%. Epithelial polyps constituted 96% of all polyps, and conventional tubular adenoma (69%) was the most common type of polyp. Advanced adenomas (intramucosal adenocarcinomas, polyp cancer) and synchronous adenocarcinomas were found to be 1.4% (16 polyps) and 0.9% (6 patients) respectively. Polyps were most frequently observed in the sigmoid colon, with a rate of 22.8%, followed by the descending colon and rectum most frequently. There was a significant association between epithelial polyps and anatomical locations (p<0.001).
In conventional colorectal adenomas, the frequency of co-occurrence of synchronous neoplasms is higher than in other polyp types.
我们旨在评估结直肠高危息肉以及同时存在的肿瘤和癌的解剖定位及人口统计学特征。
2018年7月1日至2022年7月1日期间，研究纳入了病理科诊断并接受全结肠镜检查的678例连续患者的1137份息肉切除材料。所有上皮性息肉均根据世界卫生组织《消化系统肿瘤分类》第5版（2019年）重新分类。
病例中男性占60.5%，女性占39.5%。息肉患者的平均年龄为61.1（±11.1）岁。性别与所有上皮性息肉的存在之间存在统计学显著差异（p = 0.044）。上皮性息肉在男性中比在女性中更常见（比例；男性/女性为1.58:1）。息肉的平均大小为5.2（±5.08）毫米（mm），所有息肉中86.6%小于10 mm。所有息肉中62.5%为单发息肉，37.5%为多发息肉。上皮性息肉占所有息肉的96%，传统管状腺瘤（69%）是最常见的息肉类型。高级别腺瘤（黏膜内腺癌、息肉癌）和同时性腺癌分别为1.4%（16个息肉）和0.9%（6例患者）。息肉最常出现在乙状结肠，发生率为22.8%，其次是降结肠和直肠。上皮性息肉与解剖位置之间存在显著关联（p<0.001）。
在传统的结直肠腺瘤中，同时性肿瘤的共发频率高于其他息肉类型。
