Kavas Murat, Kaymaz Serdar, Aydoğan Eroglu Selma, Karasu Ugur, Cobankara Veli, Boga Sibel
Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Turkey Department of Pulmonology.
Pamukkale Unıversity.
Sarcoidosis Vasc Diffuse Lung Dis. 2023 Mar 28;40(1):e2023002. doi: 10.36141/svdld.v40i1.13617.
Sarcoidosis, a multisystemic granulomatous disease, generally results in a lower quality of life (QoL) because of its unexpected course and diverse clinical symptoms. The Sarcoidosis Health Questionnaire (SHQ) evaluates the QoL for people with sarcoidosis in terms of their health. This study set out to validate the SHQ in a group of Turkish sarcoidosis patients.
The study included a total of 146 adult sarcoidosis patients (63 male and 83 female; mean age, 44±3.6 years; range, 27-63 years) between May 2019 and September 2021. Preparation, forward translation, reconciliation, back translation/back translation review, harmonization, finalization, and proofreading comprised the steps of the testing procedure for translation and cultural adaptation. The participants filled out three questionnaires, including the SHQ, 36-Item Short Form (SF-36) Health Survey, and King's Sarcoidosis Questionnaire (KSQ), and underwent pulmonary function tests (PFTs).
Of the patients, 95% had lung involvement, with a mean number of 1.3 organs involved. Each SHQ component displayed a moderate to high internal consistency, ranging from 0.806 to 0.844. The whole scale's Cronbach's alpha value was 0.781. The SHQ total score significantly correlated with physical component summary (p< 0.001, r=0.360) and mental component summary (p<0.001, r=0.352) scores of SF-36, and the general health status (p< 0.001, r=0.478), medication component (p<0.001, r=0.456), and eye component scores of KSQ (p<0.001, r=0.545). When patients were divided into groups based on organ involvement (p=0.01), oral steroid medication (p<0.001), and types of symptoms (P=0.021), there were significant differences in the total SHQ scores.
The Turkish version of SHQ can be a valid and accurate instrument for assessing the health of sarcoidosis patients in Turkey. When combined with normal physiological, radiological, and serological examinations, SHQ can assess the QoL of sarcoidosis patients and give useful new information.
结节病是一种多系统肉芽肿性疾病，因其病程难以预测且临床症状多样，通常会导致生活质量（QoL）降低。结节病健康问卷（SHQ）从健康角度评估结节病患者的生活质量。本研究旨在验证SHQ在一组土耳其结节病患者中的有效性。
该研究纳入了2019年5月至2021年9月期间共146例成年结节病患者（63例男性和83例女性；平均年龄44±3.6岁；范围27 - 63岁）。翻译和文化调适的测试程序步骤包括准备、正向翻译、核对、反向翻译/反向翻译审核、协调、定稿和校对。参与者填写了三份问卷，包括SHQ、36项简短健康调查（SF - 36）和国王结节病问卷（KSQ），并接受了肺功能测试（PFTs）。
患者中，95%有肺部受累，平均受累器官数为1.3个。SHQ的每个分量表显示出中等至高的内部一致性，范围从0.806至0.844。整个量表的Cronbach's alpha值为0.781。SHQ总分与SF - 36的身体分量表总分（p < 0.001，r = 0.360）和精神分量表总分（p < 0.001，r = 0.352）、KSQ的总体健康状况（p < 0.001，r = 0.478）、药物分量表（p < 0.001，r = 0.456）以及眼部分量表得分（p < 0.001，r = 0.545）显著相关。根据器官受累情况（p = 0.01）、口服类固醇药物使用情况（p < 0.001）和症状类型（P = 0.021）将患者分组时，SHQ总分存在显著差异。
土耳其语版的SHQ可以成为评估土耳其结节病患者健康状况的有效且准确的工具。当与正常的生理、放射学和血清学检查相结合时，SHQ可以评估结节病患者的生活质量并提供有用的新信息。
