Department of Intensive Care Unit, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, Jiangxi, China.
Ir J Med Sci. 2023 Dec;192(6):2769-2776. doi: 10.1007/s11845-023-03352-3. Epub 2023 Mar 28.
This study was aimed to evaluate the link between sleep characteristics and type 2 diabetes of middle-aged and elderly individuals.
Twenty thousand four hundred ninety-seven individuals enrolled in National Health and Nutritional Examination Survey (NHANES) form periods of 2005-2008 were included in this study, and 3965 individuals aged 45 years and older with complete data were detected. Variables related to sleep characteristics were analyzed by univariate analysis to identify the risk factors of type 2 diabetes, the logistic regression model was used to test for the tendency across the sections of sleep duration, and the link between sleep duration and risk of type 2 diabetes was manifested as odds ratio (OR) and 95% confidence interval (CI).
Six hundred ninety-four individuals with type 2 diabetes were identified and enrolled in the type 2 diabetes group, while the remaining individuals (n = 3271) were enrolled in the non-type 2 diabetes group. Individuals in the type 2 diabetes group (63.9 ± 10.2) were older than those in the non-type 2 diabetes group (61.2 ± 11.5, P < 0.001). Factors of taking longer time to fall asleep (P < 0.001), sleeping less (≤ 4 h) or more (≥ 9 h) (P < 0.001), having trouble in falling asleep (P = 0.001), frequent snoring (P < 0.001), frequent sleep apnea (P < 0.001), frequent nighttime awakenings (P = 0.004), and frequent excessive daytime sleepiness (P < 0.001) were linked to the risk of type 2 diabetes.
Our study revealed that sleep characteristics were closely linked to type 2 diabetes in middle-aged and elderly individuals, and a longer sleep duration might have protective effects against type 2 diabetes, but it should be constrained within 9 h/night.
本研究旨在评估中年和老年人睡眠特征与 2 型糖尿病之间的关系。
本研究纳入了参加 2005-2008 年国家健康和营养调查(NHANES)的 24997 名个体,其中 3965 名年龄在 45 岁及以上且数据完整的个体被检出。通过单变量分析来分析与睡眠特征相关的变量,以确定 2 型糖尿病的危险因素,使用逻辑回归模型来测试睡眠持续时间各节段的趋势,睡眠持续时间与 2 型糖尿病风险的关系表现为比值比(OR)和 95%置信区间(CI)。
共确定并纳入了 694 名 2 型糖尿病患者作为 2 型糖尿病组,其余(n=3271)患者纳入非 2 型糖尿病组。2 型糖尿病组患者(63.9±10.2)年龄大于非 2 型糖尿病组患者(61.2±11.5,P<0.001)。入睡时间较长(P<0.001)、睡眠较少(≤4 h)或较多(≥9 h)(P<0.001)、入睡困难(P=0.001)、打鼾频繁(P<0.001)、睡眠呼吸暂停频繁(P<0.001)、夜间频繁觉醒(P=0.004)和白天过度嗜睡频繁(P<0.001)的因素与 2 型糖尿病的风险相关。
我们的研究表明,睡眠特征与中年和老年人的 2 型糖尿病密切相关,较长的睡眠时间可能对 2 型糖尿病有保护作用,但应限制在 9 小时/夜以内。