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动物潜蚤病的治疗:有哪些新进展?

Treatment of Animal Tungiasis: What's New?

作者信息

Dos Santos Katharine Costa, Brandão Guedes Paula Elisa, Teixeira Jamille Bispo de Carvalho, Harvey Tatiani Vitor, Carlos Renata Santiago Alberto

机构信息

Departamento de Ciências Agrárias e Ambientais, Universidade Estadual de Santa Cruz (UESC), Ilhéus 45662-900, Brazil.

Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.

出版信息

Trop Med Infect Dis. 2023 Feb 27;8(3):142. doi: 10.3390/tropicalmed8030142.

Abstract

In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas , predominant in endemic areas, and , whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis.

摘要

在热带和亚热带国家,特别是在弱势社区,沙蚤病是一个严重的公共卫生问题,常常被当局忽视。流行地区常见的沙蚤以及人类感染病例较少的沙蚤是这种人畜共患病的病因。家畜是沙蚤病的潜在宿主和传播者,因此控制它们的感染将显著推动人类病例的预防工作。这篇文献综述汇编了治疗动物沙蚤病的最新研究和创新成果。文中描述了治疗动物沙蚤病的方法以及疾病控制和预防方面的研究。异恶唑啉类药物被视为治疗动物沙蚤病的有前景的药物,具有高效性和药理保护作用。鉴于狗是人类感染沙蚤病的一个重要风险因素,本文还讨论了这一发现对公共卫生的积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6d1/10051256/f7ad8e9ffa55/tropicalmed-08-00142-g001.jpg

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