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司罗南用于治疗自然感染犬的潜蚤病。

Use of sarolaner in the treatment of tungiasis in naturally infested dogs.

作者信息

Tortoriello Rafaella, Lopes Natália Lôres, Linhares Bianca Bianco Paschoalino, Correia Thais Ribeiro, Fernandes Julio Israel

机构信息

Veterinarian, MSc., Programa de Pós-Graduação em Ciências Veterinárias (PPGCV), Departamento de Parasitologia Animal (DPA) Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.

Veterinarian, DSc., Programa de Pós-Graduação em Medicina Veterinária (PPGMV), Departamento de Medicina e Cirurgia Veterinária (DMCV), UFRRJ, Seropédica, RJ, Brazil.

出版信息

Braz J Vet Med. 2024 Mar 13;46:e000224. doi: 10.29374/2527-2179.bjvm000224. eCollection 2024.

Abstract

Tungiasis is an endemic dermatological parasitic zoonosis in Latin America, caused by the sand flea spp (Siphonaptera, Tungidae), which promotes intense discomfort, swelling, erythema, itching, pain, secondary bacterial infection, cellulitis and necrosis. Sarolaner has been used to control different ectoparasites, but there is no record of its use for the treatment of tungiasis in dogs. The objective of this study was to evaluate the effectiveness of sarolaner for the treatment dogs naturally infested by spp kept in the same infested environment. Three of four animals were medicated with sarolaner orally with a single dose of 2 mg/kg, as recommended by the manufacturer, and one animal remained without medication. After 24 hours, the fleas from all four dogs were mechanically removed. The animals were reevaluated on days +15 and +30 to assess possible reinfestation. The medicated animals remained free of fleas, while the untreated animal had fleas on the days previously defined for reevaluation. We can thus conclude that the use of sarolaner is an effective choice for tungiasis treatment.

摘要

潜蚤病是拉丁美洲一种地方性皮肤寄生性人畜共患病,由沙蚤属(蚤目,潜蚤科)引起,会导致强烈不适、肿胀、红斑、瘙痒、疼痛、继发性细菌感染、蜂窝织炎和坏死。沙罗拉纳已被用于控制不同的体外寄生虫,但尚无其用于治疗犬类潜蚤病的记录。本研究的目的是评估沙罗拉纳对生活在同一感染环境中自然感染沙蚤属的犬类的治疗效果。四只动物中有三只按照制造商的建议口服单剂量2mg/kg的沙罗拉纳进行药物治疗,一只动物未用药。24小时后,对所有四只狗身上的跳蚤进行机械清除。在第15天和第30天对动物进行重新评估,以评估可能的再次感染情况。用药的动物身上没有跳蚤,而未治疗的动物在之前确定的重新评估日期有跳蚤。因此,我们可以得出结论,使用沙罗拉纳是治疗潜蚤病的有效选择。

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