Muinde Patrick, Maina John, Momanyi Kelvin, Yamo Victor, Mwaniki John, Kiiru John
World Animal Protection, Westside Towers, 9th Floor, Suite 901, Along Lower Kabete Road, Westlands, P.O. Box 66580, Nairobi 00800, Kenya.
Center for Microbiology Research, Kenya Medical Research Institute (KEMRI), P.O. Box 54840, Nairobi 00200, Kenya.
Antibiotics (Basel). 2023 Mar 20;12(3):613. doi: 10.3390/antibiotics12030613.
There is increasing proof of bacterial resistance to antibiotics all over the world, and this puts the effectiveness of antimicrobials that have been essential in decreasing disease mortality and morbidity at stake. The WHO has labeled some classes of antimicrobials as vitally important to human health. Bacteria from animals are thought to be reservoirs of resistance genes that can be transferred to humans through the food chain. This study aimed to identify the resistance patterns of bacteria from pork and poultry meat samples purchased from leading retail outlets in Kenya. Of the 393 samples collected, 98.4% of pork and 96.6% of poultry were contaminated with high levels of bacteria. Among the 611 bacterial isolates recovered, 38.5% were multi-drug resistant. This resistance was noted for critically essential antimicrobials (according to the WHO) such as rifampicin (96%), ampicillin (35%), cefotaxime (9%), cefepime (6%), and ciprofloxacin (6%). Moreover, there was high resistance to key antimicrobials for veterinary medicine such as tetracycline (39%), sulfamethoxazole (33%), and trimethoprim (30%). It is essential to spread awareness about the judicious use of antibiotics and take preventive measures to reduce disease burden.
全球范围内,细菌对抗生素产生耐药性的证据越来越多,这危及了在降低疾病死亡率和发病率方面至关重要的抗菌药物的有效性。世界卫生组织已将某些类别的抗菌药物列为对人类健康至关重要的药物。来自动物的细菌被认为是耐药基因的储存库,这些基因可通过食物链转移给人类。本研究旨在确定从肯尼亚主要零售网点购买的猪肉和禽肉样本中细菌的耐药模式。在收集的393个样本中,98.4%的猪肉和96.6%的禽肉被大量细菌污染。在回收的611株细菌分离物中,38.5%具有多重耐药性。对诸如利福平(96%)、氨苄西林(35%)、头孢噻肟(9%)、头孢吡肟(6%)和环丙沙星(6%)等(根据世界卫生组织)极为重要的抗菌药物都发现了这种耐药性。此外,对四环素(39%)、磺胺甲恶唑(33%)和甲氧苄啶(30%)等兽用关键抗菌药物也有很高的耐药性。有必要提高人们对合理使用抗生素的认识,并采取预防措施以减轻疾病负担。