Drakouli Artemis-Eirini, Kontele Ioanna, Poulimeneas Dimitrios, Saripanagiotou Stella, Grammatikopoulou Maria G, Sergentanis Theodoros N, Vassilakou Tonia
Department of Public Health Policy, School of Public Health, University of West Attica, 196 Alexandras Avenue, 11521 Athens, Greece.
Department of Nutrition and Dietetics, University of the Peloponnese, 24100 Kalamata, Greece.
Children (Basel). 2023 Feb 23;10(3):433. doi: 10.3390/children10030433.
Recently, besides the focus on the medical diagnosis and therapeutic interventions for food allergy (FA), the psychosocial aspects of this frequent condition have also been investigated. The current systematic review aimed to explore and synthesize the scientific evidence published from January 2015 to April 2022 on Health-Related Quality of Life (HRQoL) among children and adolescents with FAs. Twenty-eight research studies were included in the review, which was conducted on three databases (PubMed, Scopus and Cochrane Library). In most studies, the scores indicate an average level of HRQoL for children and adolescents with FAs, with girls and older children being more negatively affected than boys and younger ones, respectively. Few studies compared HRQoL between children with FA and healthy children, with 3 of them showing worse HRQoL for children with FAs. Immunotherapy has been found to improve the QoL of children with FAs. Anaphylaxis history, number of FAs, additional allergies, number and severity of symptoms were identified as the main factors with a negative impact on QoL. More comparative studies on the HRQoL of children and adolescents with FAs and healthy populations or children with other chronic diseases are required in order to improve QoL of children with FAs.
最近，除了关注食物过敏（FA）的医学诊断和治疗干预措施外，这种常见病症的心理社会方面也受到了研究。当前的系统评价旨在探索和综合2015年1月至2022年4月期间发表的关于FA患儿和青少年健康相关生活质量（HRQoL）的科学证据。该评价纳入了28项研究，这些研究是在三个数据库（PubMed、Scopus和Cochrane图书馆）上进行的。在大多数研究中，评分表明FA患儿和青少年的HRQoL处于平均水平，女孩和年龄较大的儿童分别比男孩和年龄较小的儿童受到的负面影响更大。很少有研究比较FA患儿和健康儿童的HRQoL，其中3项研究表明FA患儿的HRQoL较差。已发现免疫疗法可改善FA患儿的生活质量。过敏反应史、FA的数量、其他过敏情况、症状的数量和严重程度被确定为对生活质量有负面影响的主要因素。为了改善FA患儿的生活质量，需要对FA患儿和青少年与健康人群或其他慢性病患儿的HRQoL进行更多的比较研究。
