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儿童和青少年食物过敏负担:系统评价。

The burden of food allergy on children and teens: A systematic review.

机构信息

Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.

Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Pediatr Allergy Immunol. 2022 Mar;33(3):e13743. doi: 10.1111/pai.13743.

Abstract

BACKGROUND

Over the last two decades, researchers have placed increasing attention on understanding how food allergy affects the health-related quality of life (HRQL) and psychosocial well-being of children and teens. In response, a number of reviews have been published that aim at synthesizing the literature. However, many of these papers focus narrowly on HRQL or suffer from methodological limitations.

METHOD

The current review aims to fill this gap by providing a comprehensive overview of the burden of pediatric food allergy by synthesizing the quantitative and qualitative literature.

RESULTS

Findings from the present review provide evidence of reduced HRQL among children and teens with food allergy, particularly older children and those with more severe manifestations of the condition. In comparison to HRQL, the link between food allergy and psychosocial functioning is less clear; however, some evidence can be cited linking food allergy to greater levels of psychological distress. Qualitative evidence suggests that the burden of pediatric food allergy largely stems from worries surrounding exposures outside of the home and the social consequences of the condition. The current review also highlights several gaps in the literature, including a paucity of longitudinal research, research focused on predictors of psychological distress among children and teens with food allergy as well as a dearth of studies comparing rates of bullying in food-allergic and non-food-allergic samples.

CONCLUSION

More emphasis should be placed on not only alleviating the social and psychological consequences of food allergy, but also on identifying and assisting those most acutely burdened by the condition.

摘要

背景

在过去的二十年中,研究人员越来越关注了解食物过敏如何影响儿童和青少年的健康相关生活质量(HRQL)和心理健康。为此,已经发表了许多旨在综合文献的评论。然而,许多这些论文都狭隘地关注 HRQL 或存在方法学上的局限性。

方法

本综述旨在通过综合定量和定性文献,全面概述儿科食物过敏的负担,从而填补这一空白。

结果

本综述的研究结果提供了证据表明,食物过敏的儿童和青少年的 HRQL 降低,特别是年龄较大的儿童和病情更严重的儿童。与 HRQL 相比,食物过敏与心理社会功能之间的联系不太清楚;但是,可以引用一些证据表明食物过敏与更高水平的心理困扰有关。定性证据表明,儿科食物过敏的负担主要源于对家庭以外暴露的担忧以及该疾病的社会后果。本综述还强调了文献中的几个空白,包括缺乏纵向研究、专注于食物过敏儿童和青少年心理困扰预测因素的研究以及缺乏比较食物过敏和非食物过敏样本中欺凌率的研究。

结论

应该更加重视减轻食物过敏的社会和心理后果,以及确定和帮助那些受该疾病负担最严重的人。

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