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黄斑到视盘中心框架改变下的视网膜血管局部迂曲度

Retinal Vessel Local Tortuosity under a Macula-to-Optic Disc Central-Framing Change.

作者信息

Ramírez Natalia, Ralló Miquel, Millan Maria S

机构信息

Applied Optics and Image Processing Group (GOAPI), Universitat Politècnica de Catalunya-BarcelonaTech, ViolinistaVellsolà 37, 08222 Terrassa, Barcelona, Spain.

出版信息

Diagnostics (Basel). 2023 Mar 8;13(6):1030. doi: 10.3390/diagnostics13061030.

DOI:10.3390/diagnostics13061030
PMID:36980338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10046985/
Abstract

Some ocular and cardiovascular diseases can be detected through the increased tortuosity of retinal blood vessels. Objective tortuosity measures can be obtained from digital image analysis of a retinography. This study tested a set of local tortuosity indices under a change in the frame center (macula, optic disc) of the eye fundus image. We illustrate the effects of such a change on 40 pairs of vessels evaluated with eight tortuosity indices. We show that the frame center change caused significant differences in the mean values of the vast majority of the tortuosity indices analyzed. The index defined as the ratio of the curvature to the arc length of a vessel segment proved to be the most robust in relation to a frame center change. Experimental results obtained from the analysis of clinical images are provided and discussed.

摘要

一些眼部和心血管疾病可通过视网膜血管迂曲度增加来检测。客观的迂曲度测量可通过视网膜造影的数字图像分析获得。本研究在眼底图像的帧中心（黄斑、视盘）变化的情况下测试了一组局部迂曲度指标。我们说明了这种变化对用八个迂曲度指标评估的40对血管的影响。我们表明，帧中心变化在绝大多数分析的迂曲度指标的平均值上引起了显著差异。被定义为血管段曲率与弧长之比的指标在帧中心变化方面被证明是最稳健的。提供并讨论了从临床图像分析中获得的实验结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/ac1fcb4557a0/diagnostics-13-01030-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/a58b040f0cb5/diagnostics-13-01030-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/79fc3bc5545b/diagnostics-13-01030-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/ac76506d739d/diagnostics-13-01030-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/e1f2047b1aac/diagnostics-13-01030-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/52208757fa81/diagnostics-13-01030-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/1962be171de4/diagnostics-13-01030-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/ac1fcb4557a0/diagnostics-13-01030-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/a58b040f0cb5/diagnostics-13-01030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/a09a85e66dd8/diagnostics-13-01030-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/d3535e1aaefc/diagnostics-13-01030-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/351229c57129/diagnostics-13-01030-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/79fc3bc5545b/diagnostics-13-01030-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/ac76506d739d/diagnostics-13-01030-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/e1f2047b1aac/diagnostics-13-01030-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/52208757fa81/diagnostics-13-01030-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/1962be171de4/diagnostics-13-01030-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/10046985/ac1fcb4557a0/diagnostics-13-01030-g010.jpg

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Eye (Lond). 2021 Jan;35(1):149-161. doi: 10.1038/s41433-020-01233-y. Epub 2020 Oct 24.
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Computational assessment of the retinal vascular tortuosity integrating domain-related information.计算评估视网膜血管迂曲度，整合域相关信息。
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Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease.
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