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通过倾向得分匹配法基于患者报告结局评估髋关节和膝关节置换手术的快速康复路径

Assessment of Fast-Track Pathway in Hip and Knee Replacement Surgery by Propensity Score Matching on Patient-Reported Outcomes.

作者信息

Campagner Andrea, Milella Frida, Guida Stefania, Bernareggi Susan, Banfi Giuseppe, Cabitza Federico

机构信息

IRCCS Istituto Ortopedico Galeazzi, 20157 Milano, Italy.

Faculty of Medicine and Surgery, Università Vita-Salute San Raffaele, 20132 Milano, Italy.

出版信息

Diagnostics (Basel). 2023 Mar 21;13(6):1189. doi: 10.3390/diagnostics13061189.

Abstract

Total hip (THA) and total knee (TKA) arthroplasty procedures have steadily increased over the past few decades, and their use is expected to grow further, mainly due to an increasing number of elderly patients. Cost-containment strategies, supporting a rapid recovery with a positive functional outcomes, high patient satisfaction, and enhanced patient reported outcomes, are needed. A Fast Track surgical procedure (FT) is a coordinated perioperative approach aimed at expediting early mobilization and recovery following surgery and, accordingly, shortening the length of hospital stay (LOS), convalescence and costs. In this view, rapid rehabilitation surgery optimizes traditional rehabilitation methods by integrating evidence-based practices into the procedure. The aim of the present study was to compare the effectiveness of Fast Track versus Care-as-Usual surgical procedures and pathways (including rehabilitation) on a mid-term patient-reported outcome (PROs), the SF12 (with regard both to Physical and Mental Scores), 3 months after hip or knee replacement surgery, with the use of Propensity score-matching (PSM) analysis to address the issue of the comparability of the groups in a non-randomized study. We were interested in the evaluation of the entire pathways, including the postoperative rehabilitation stage, therefore, we only used early home discharge as a surrogate to differentiate between the Fast Track and Care-as-Usual rehabilitation pathways. Our study shows that the entire Fast Track pathway, which includes the post-operative rehabilitation stage, has a significantly positive impact on physical health-related status (SF12 Physical Scores), as perceived by patients 3 months after hip or knee replacement surgery, as opposed to the standardized program, both in terms of the PROs score and the relative improvements observed, as compared with the minimum clinically important difference. This result encourages additional research into the effects of Fast Track rehabilitation on the entire process of care for patients undergoing hip or knee arthroplasty, focusing only on patient-reported outcomes.

摘要

在过去几十年中,全髋关节置换术(THA)和全膝关节置换术(TKA)的手术数量稳步增加,并且由于老年患者数量的不断增加,预计其使用量还将进一步增长。因此,需要采取成本控制策略,以实现快速康复,并取得良好的功能结果、较高的患者满意度以及更好的患者报告结局。快速康复外科手术(FT)是一种围手术期协调方案,旨在加快术后早期活动和康复,从而缩短住院时间(LOS)、康复期并降低成本。从这个角度来看,快速康复手术通过将循证实践融入手术过程,优化了传统的康复方法。本研究的目的是比较快速康复与常规护理手术程序及路径(包括康复)对髋关节或膝关节置换手术后3个月患者报告结局(PROs)——SF12(包括身体和心理评分)的中期效果,并使用倾向得分匹配(PSM)分析来解决非随机研究中组间可比性的问题。我们关注的是整个路径,包括术后康复阶段,因此,我们仅将早期出院作为区分快速康复和常规护理康复路径的替代指标。我们的研究表明,包括术后康复阶段的整个快速康复路径,对髋关节或膝关节置换手术后3个月患者所感知的与身体健康相关的状况(SF12身体评分)有显著的积极影响,与标准化方案相比,在PROs评分以及观察到的相对改善方面,均与最小临床重要差异相比更具优势。这一结果鼓励进一步研究快速康复对接受髋关节或膝关节置换术患者的整个护理过程的影响,且仅关注患者报告的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24ed/10047673/aaa59515eeaf/diagnostics-13-01189-g001.jpg

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