Chaleil D, Simon P, Tessier B, Cartier F, Allain P
Clin Chim Acta. 1986 Apr 15;156(1):105-8. doi: 10.1016/0009-8981(86)90185-3.
Blood plasma fluoride was determined in 15 chronic haemodialysed patients (60.2 +/- 7.2 yr old) before and after a 4-h dialysis using dialysates with very low fluoride level, and in two control groups, the first of 20 healthy younger subjects (45.9 +/- 3.4 yr old), the second of 8 healthy older subjects (69.1 +/- 6.8 y old). Before haemodialysis the fluoride concentration (1.31 +/- 0.31 mumol/l; 24.8 +/- 5.9 micrograms/l), was higher than in both control groups (0.35 +/- 0.16 mumol/l; 6.6 +/- 3.1 micrograms/l and 0.44 +/- 0.16 mumol/l 8.4 +/- 3.0 micrograms/l, respectively). During dialysis, the mean fluoride concentration fell to 0.94 +/- 0.26 mumol/l, remaining however, significantly higher than in control subjects. The use of fluoride-free dialysates seems to partially compensate the effect of renal impairment since plasma fluoride is only moderately increased in these patients.
对15例慢性血液透析患者（年龄60.2±7.2岁）在使用氟含量极低的透析液进行4小时透析前后测定了血浆氟，并与两个对照组进行了比较，第一组为20名健康年轻受试者（年龄45.9±3.4岁），第二组为8名健康老年受试者（年龄69.1±6.8岁）。血液透析前，氟浓度（1.31±0.31μmol/L；24.8±5.9μg/L）高于两个对照组（分别为0.35±0.16μmol/L；6.6±3.1μg/L和0.44±0.16μmol/L；8.4±3.0μg/L）。透析期间，平均氟浓度降至0.94±0.26μmol/L，但仍显著高于对照组。使用无氟透析液似乎部分补偿了肾功能损害的影响，因为这些患者的血浆氟仅适度升高。
