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γ-氨基丁酸的代谢、转运及其在植物非生物胁迫(缺氧、盐、干旱)抗性调控中的作用和机制

GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants.

作者信息

Yuan Ding, Wu Xiaolei, Gong Binbin, Huo Ruixiao, Zhao Liran, Li Jingrui, Lü Guiyun, Gao Hongbo

机构信息

Collaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.

出版信息

Metabolites. 2023 Feb 26;13(3):347. doi: 10.3390/metabo13030347.

Abstract

γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance.

摘要

γ-氨基丁酸(GABA)是一种普遍存在的四碳非蛋白质氨基酸。在植物中,GABA存在于不同的细胞区室中,并执行不同的代谢功能。作为一种信号分子,GABA参与各种非生物胁迫耐受性的调节。许多研究发现,当植物遭受非生物胁迫时,GABA会大量积累,这已通过科学网、PubMed、爱思唯尔等数据库得到证实。GABA通过调节细胞内pH值、离子转运、激活抗氧化系统和清除活性氧来增强植物对非生物胁迫的耐受性。在GABA发挥作用的过程中,转运对于GABA在细胞中的积累和代谢途径非常重要。因此,研究转运蛋白介导GABA跨细胞膜和细胞器膜的转运是一个值得关注的方向。本文描述了GABA在植物中的分布、生物合成和分解代谢。此外,我们重点关注外源GABA转运研究的最新进展以及在调节非生物胁迫响应中的功能和机制。基于对GABA在抵抗各种非生物胁迫中作用的总结,我们得出结论,GABA已成为提高植物非生物耐受性的有效化合物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a053/10051757/73cbeedef673/metabolites-13-00347-g001.jpg

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