• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

自行研发的低成本吲哚菁绿相机在手术成像中的应用——单机构经验。

Application of a Self-developed, Low-budget Indocyanine Green Camera in Surgical Imaging - a Single Institution's Experiences.

机构信息

Department of Surgery, University of Pécs, Pécs, Hungary.

Department of Biophysics, University of Pécs, Pécs, Hungary.

出版信息

J Fluoresc. 2023 Sep;33(5):2099-2103. doi: 10.1007/s10895-023-03224-0. Epub 2023 Mar 29.

DOI:10.1007/s10895-023-03224-0
PMID:36988781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10539407/
Abstract

INTRODUCTION

Indocyanine green is a fluorescent dye, the use of which is becoming more and more widespread in different areas of surgery. Several international studies deal with the dye's usefulness in intraoperative angiography, the localization of tumors, the more precise identification of anatomical structures, the detection of lymph nodes and lymph ducts, etc. The application of the dye is safe, but a suitable equipment park is required for its use, which entails relatively high costs.

OBJECTIVES

The aim of our research is to create a detector system on a low budget, to be used safely in everyday practice and to illustrate its operation with practical examples at our own institute.

METHODS

By modifying a web camera, using filter lenses and special LEDs, we created a device suitable for exciting and detecting indocyanine green fluorescence. We prove its excellent versatility during the following procedures at our institute: breast tumor surgery, kidney transplantation, bowel resection, parathyroid surgery and liver tumor resection.

RESULTS

The finished camera has an LED light source with a peak wavelength of 780 nm, and the incoming light is filtered by a bandpass filter with a center wavelength of 832 nm. A low budget ($112), easy-to-use tool was created, which is suitable for taking advantage of the opportunities provided by indocyanine green.

摘要

简介

吲哚菁绿是一种荧光染料,其在不同外科领域的应用越来越广泛。多项国际研究涉及该染料在术中血管造影、肿瘤定位、更精确地识别解剖结构、淋巴结和淋巴管检测等方面的用途。该染料的应用是安全的,但需要合适的设备才能使用,这需要相对较高的成本。

目的

我们的研究旨在创建一个低成本的探测器系统,使其在日常实践中安全使用,并在我们自己的研究所中用实际例子来说明其操作。

方法

通过修改网络摄像头,使用滤光片和特殊的 LED,我们创建了一个适合激发和检测吲哚菁绿荧光的设备。我们在研究所的以下程序中证明了其出色的多功能性:乳腺肿瘤手术、肾移植、肠道切除术、甲状旁腺手术和肝肿瘤切除术。

结果

成品摄像头有一个峰值波长为 780nm 的 LED 光源,输入的光通过中心波长为 832nm 的带通滤波器进行过滤。我们创建了一个低成本(112 美元)、易于使用的工具,可充分利用吲哚菁绿带来的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10539407/539ab4b6eea8/10895_2023_3224_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10539407/539ab4b6eea8/10895_2023_3224_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10539407/539ab4b6eea8/10895_2023_3224_Fig1_HTML.jpg

相似文献

1
Application of a Self-developed, Low-budget Indocyanine Green Camera in Surgical Imaging - a Single Institution's Experiences.自行研发的低成本吲哚菁绿相机在手术成像中的应用——单机构经验。
J Fluoresc. 2023 Sep;33(5):2099-2103. doi: 10.1007/s10895-023-03224-0. Epub 2023 Mar 29.
2
Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial.近红外荧光法探测宫颈癌和子宫癌患者前哨淋巴结的研究(FILM):一项随机、3 期、多中心、非劣效性临床试验。
Lancet Oncol. 2018 Oct;19(10):1394-1403. doi: 10.1016/S1470-2045(18)30448-0. Epub 2018 Aug 22.
3
New Advances of ICG Angiography in Parathyroid Identification.吲哚菁绿血管造影术在甲状旁腺识别中的新进展
Endocr Metab Immune Disord Drug Targets. 2019;19(7):936-940. doi: 10.2174/1871530319666190206212456.
4
Fluorescence navigation with indocyanine green for detecting sentinel lymph nodes in breast cancer.用于检测乳腺癌前哨淋巴结的吲哚菁绿荧光导航技术。
Breast Cancer. 2005;12(3):211-5. doi: 10.2325/jbcs.12.211.
5
Intraoperative Fluorescence Imaging for Detection of Sentinel Lymph Nodes and Lymphatic Vessels during Open Prostatectomy using Indocyanine Green.术中荧光成像在使用吲哚菁绿的开放性前列腺切除术期间检测前哨淋巴结和淋巴管。
J Urol. 2015 Aug;194(2):371-7. doi: 10.1016/j.juro.2015.01.008. Epub 2015 Jan 10.
6
Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging.吲哚菁绿荧光成像在胃癌手术中检测前哨淋巴结:与红外成像的比较
Ann Surg Oncol. 2008 Jun;15(6):1640-3. doi: 10.1245/s10434-008-9872-7. Epub 2008 Apr 1.
7
Multispectrum Indocyanine Green Videography for Visualizing Brain Vascular Pathology.多谱段吲哚菁绿视频成像在脑血管病变可视化中的应用
World Neurosurg. 2019 Dec;132:e545-e553. doi: 10.1016/j.wneu.2019.08.078. Epub 2019 Aug 20.
8
Potential of indocyanine green near-infrared fluorescence imaging in experimental and clinical practice.吲哚菁绿近红外荧光成像在实验和临床实践中的应用潜力。
Photodiagnosis Photodyn Ther. 2018 Dec;24:292-299. doi: 10.1016/j.pdpdt.2018.10.011. Epub 2018 Oct 16.
9
Laparoscopic detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging.腹腔镜下胃癌手术中吲哚菁绿荧光成像引导前哨淋巴结检测。
Surg Endosc. 2011 May;25(5):1672-6. doi: 10.1007/s00464-010-1405-3. Epub 2010 Oct 26.
10
Use of fluorescence imaging and indocyanine green during thyroid and parathyroid surgery: Results of an intercontinental, multidisciplinary Delphi survey.甲状腺和甲状旁腺手术中荧光成像和吲哚菁绿的应用:一项洲际多学科德尔菲调查的结果。
Surgery. 2022 Dec;172(6S):S6-S13. doi: 10.1016/j.surg.2022.09.004.

本文引用的文献

1
Indocyanine Green Fluorescence Guided Surgery in Colorectal Surgery.吲哚菁绿荧光引导在结直肠手术中的应用
J Clin Med. 2023 Jan 7;12(2):494. doi: 10.3390/jcm12020494.
2
Does Using Indocyanine Green Fluorescence Imaging for Tumors Help in Determining the Safe Surgical Margin in Real-Time Navigation of Laparoscopic Hepatectomy? A Retrospective Study.使用吲哚菁绿荧光成像技术实时导航腹腔镜肝切除术中的肿瘤是否有助于确定安全的手术切缘?一项回顾性研究。
Ann Surg Oncol. 2023 Apr;30(4):1981-1987. doi: 10.1245/s10434-022-12893-3. Epub 2022 Dec 9.
3
Educational Review: Intraoperative Parathyroid Fluorescence Detection Technology in Thyroid and Parathyroid Surgery.
教育综述:甲状腺和甲状旁腺手术中的术中甲状旁腺荧光检测技术
Ann Surg Oncol. 2023 Feb;30(2):973-993. doi: 10.1245/s10434-022-12807-3. Epub 2022 Dec 8.
4
Indocyanine Green Is a Safe and Effective Alternative to Radioisotope in Breast Cancer Sentinel Lymph Node Biopsy regardless of Patient Body Mass Index.吲哚菁绿在乳腺癌前哨淋巴结活检中是一种安全有效的放射性同位素替代物,与患者的体重指数无关。
Eur Surg Res. 2023;64(2):230-236. doi: 10.1159/000528155. Epub 2022 Nov 21.
5
Investigation of Different Methods of Intraoperative Graft Perfusion Assessment during Kidney Transplantation for the Prediction of Delayed Graft Function: A Prospective Pilot Trial.肾移植术中不同移植物灌注评估方法对移植肾功能延迟恢复预测的研究:一项前瞻性试点试验
J Pers Med. 2022 Oct 21;12(10):1749. doi: 10.3390/jpm12101749.
6
Precise diagnosis of acute mesenteric ischemia using indocyanine green imaging prevents small bowel resection: A case report.使用吲哚菁绿成像精确诊断急性肠系膜缺血可避免小肠切除:一例报告
Int J Surg Case Rep. 2022 Aug;97:107463. doi: 10.1016/j.ijscr.2022.107463. Epub 2022 Jul 30.
7
Indocyanine green: An old drug with novel applications.吲哚菁绿:一种具有新应用的老药。
Tzu Chi Med J. 2021 Apr 1;33(4):317-322. doi: 10.4103/tcmj.tcmj_216_20. eCollection 2021 Oct-Dec.
8
Laparoscopic sentinel node navigation surgery versus laparoscopic gastrectomy with lymph node dissection for early gastric cancer: short-term outcomes of a multicentre randomized controlled trial (SENORITA).腹腔镜前哨淋巴结导航手术与腹腔镜胃癌淋巴结清扫术治疗早期胃癌的短期疗效:多中心随机对照试验(SENORITA)
Br J Surg. 2020 Oct;107(11):1429-1439. doi: 10.1002/bjs.11655. Epub 2020 Jun 3.
9
Randomized Trial of Near-infrared Incisionless Fluorescent Cholangiography.随机对照试验近红外无切口荧光胆管造影术。
Ann Surg. 2019 Dec;270(6):992-999. doi: 10.1097/SLA.0000000000003178.
10
Clinical utility of the additional use of blue dye for indocyanine green for sentinel node biopsy in breast cancer.在乳腺癌前哨淋巴结活检中额外使用蓝色染料辅助吲哚菁绿的临床效用。
J Surg Res. 2017 Jul;215:88-92. doi: 10.1016/j.jss.2017.03.038. Epub 2017 Apr 1.