State Key Laboratory of Advanced Optical Communication Systems and Networks, School of Electronics, and Center for Quantum Information Technology, Peking University, Beijing 100871, China.
Sci Adv. 2023 Mar 29;9(13):eadg1746. doi: 10.1126/sciadv.adg1746.
Magnetocardiography (MCG), which uses high-sensitivity magnetometers to record magnetic field signals generated by electrical activity in the heart, is a noninvasive method for evaluating heart diseases such as arrhythmia and ischemia. The MCG measurements usually require the participant keeping still in a magnetically shielded room due to the immovable sensor and noisy external environments. These requirements limit MCG applications, such as exercise MCG tests and long-term MCG observations, which are useful for early detections of heart diseases. Here, we introduce a movable MCG system that can clearly record MCG signals of freely behaving participants in an unshielded environment. On the basis of optically pumped magnetometers with a sensitivity of 140 fT/Hz, we successfully demonstrated the resting MCG and the exercise MCG tests. Our method is promising to realize a practical movable multichannel unshielded MCG system that nearly sets no limits to participants and brings another kind of insight into the medical diagnosis of heart disease.
磁心图（MCG）使用高灵敏度的磁力计来记录心脏电活动产生的磁场信号，是一种评估心律失常和缺血等心脏疾病的非侵入性方法。由于传感器不可移动和外部环境嘈杂，MCG 测量通常需要参与者在磁屏蔽室内保持静止。这些要求限制了 MCG 的应用，例如运动 MCG 测试和长期 MCG 观察，这些测试对于早期发现心脏病很有用。在这里，我们介绍了一种可移动的 MCG 系统，它可以在非屏蔽环境中清晰地记录自由活动参与者的 MCG 信号。在灵敏度为 140 fT/Hz 的光泵磁力计的基础上，我们成功地演示了静息 MCG 和运动 MCG 测试。我们的方法有望实现一种实用的可移动多通道非屏蔽 MCG 系统，该系统对参与者几乎没有限制，并为心脏病的医学诊断带来另一种见解。
