Pol'shin V V, Shelegiia G Sh, Mkhitarov V A
Fiziol Zh SSSR Im I M Sechenova. 1986 Feb;72(2):221-3.
In the female rat blood, prior to and 5, and 50 days after bilateral ovarectomy with the substitutional administration of 50 units of folliculin and estradiol--dipropionate subcutaneously every 48 hrs for 50 days, a progressing decrease of the phagocytic activity was observed. Under the effect of estradiol--dipropionate the phagocytic activity reduced after ovarectomy was gradually returning to the initial level, whereas under the effect of folliculin the phagocytic activity increased proportionally to the time of incubation of blood with Staphylococcus aureus bacterial areas. The phagocytic activity of the blood neutrophiles seems to depend on estrogens.
