Department of Chemistry, University of Education, Ho Chi Minh City, Vietnam.
Faculty of Chemical Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nat Prod Res. 2024 Aug;38(15):2603-2608. doi: 10.1080/14786419.2023.2193746. Epub 2023 Mar 31.
A new depsidone, parmoferone A (), together with three known compounds, parmosidone K (), albifolione (), and 4-chloroorcinol () were isolated from the lichen (Taylor) Hale (Parmeliaceae). The structures of isolated compounds were identified from its spectroscopic data and by comparison with the literature. Compounds were evaluated for alpha-glucosidase inhibition. Compound was determined to be a potent non-competitive inhibitor against alpha-glucosidase with an IC value of 18.1 μM.
从地衣 （Taylor）Hale（Parmeliaceae）中分离得到一种新的去甲二萜， Parmoferone A（），以及三种已知化合物， Parmosidone K（），albifolione（）和 4-氯邻苯二酚（）。从其光谱数据和与文献的比较确定了分离化合物的结构。对分离得到的化合物进行了α-葡萄糖苷酶抑制活性评价。化合物 被确定为一种有效的非竞争性α-葡萄糖苷酶抑制剂，IC 值为 18.1 μM。
