Thomas A H, Newland P
J Chromatogr. 1986 Feb 28;354:317-24. doi: 10.1016/s0021-9673(01)87032-1.
Thin-layer chromatography and high-performance liquid chromatography have been used to separate and characterize representatives of the aromatic heptaene group of antifungal antibiotics. Most antibiotics were complex mixtures that could be placed in well defined groups. The identity of candicidin and levorin was confirmed in one group. Aureofungin, DJ400 and hamycin shared many components in common in the second group. The proportion of the individual components of lucknomycin and trichomycin was markedly different from each other and from the antibiotics in the other two groups. Lucknomycin stood out as the most homogeneous of the antibiotics examined.
薄层色谱法和高效液相色谱法已被用于分离和鉴定抗真菌抗生素芳香族庚烯类的代表物。大多数抗生素是复杂的混合物，可分为明确的类别。在一组中确认了杀假丝菌素和左菌素的特性。在第二组中，金褐霉素、DJ400和哈霉素有许多共同成分。鲁克那霉素和曲古霉素的各个成分比例彼此明显不同，也与其他两组中的抗生素不同。鲁克那霉素是所检测抗生素中最均一的。
