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一名相对年轻的人因新冠病毒感染引发谵妄

Delirium in a Relatively Young Person due to COVID-19 Infection.

作者信息

Das Soumitra, Melgar Pablo, Rasool Aniqa Abdul, Adhikari Adarsha, Patel Rudresh, Adre Lorenzo Abednego B, Lopez Marylaine J

机构信息

Royal Melbourne Hospital, Australia.

Aga Khan University, Karachi, Pakistan.

出版信息

Case Rep Psychiatry. 2023 Mar 23;2023:6215386. doi: 10.1155/2023/6215386. eCollection 2023.

DOI:10.1155/2023/6215386
PMID:37006446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10063355/
Abstract

The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2 virus), has significantly impacted global health. It can present a range of complications, from asymptomatic to severe respiratory distress syndrome. It has also been linked to complications in multiple organ systems, including neurological symptoms such as headaches and encephalopathy. Delirium, characterized by acute confusion, is common in older adults and associated with prolonged hospital stays and elevated mortality rates. We present a case study of a young mother with a prior medical history of mild to moderate depression who experienced an episode of delirium consequent to a COVID-19 infection. The initial manifestation of her illness was mild diarrhea, but as her condition worsened, she began exhibiting symptoms of delirium. These symptoms include confusion, agitation, sleep disturbance, and disordered behavior. The delirious episode was brief and effectively managed with small doses of psychotropic medications to control aggressive behavior. Upon resolution, no additional treatment was deemed necessary. This case underscores the wide-ranging effects of COVID-19 on physical and psychological well-being and highlights the importance of considering symptoms beyond those associated with respiratory distress.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2病毒)引起的冠状病毒病(COVID-19)大流行对全球健康产生了重大影响。它可表现出一系列并发症,从无症状到严重呼吸窘迫综合征。它还与多个器官系统的并发症有关,包括头痛和脑病等神经症状。以急性意识混乱为特征的谵妄在老年人中很常见,并且与住院时间延长和死亡率升高有关。我们介绍了一个病例研究,对象是一位有轻度至中度抑郁症病史的年轻母亲,她在感染COVID-19后出现了谵妄发作。她疾病的最初表现是轻度腹泻,但随着病情恶化,她开始出现谵妄症状。这些症状包括意识混乱、躁动、睡眠障碍和行为紊乱。谵妄发作短暂,通过小剂量精神药物有效控制攻击性行为。发作结束后,无需额外治疗。该病例强调了COVID-19对身心健康的广泛影响,并突出了考虑呼吸窘迫以外症状的重要性。

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本文引用的文献

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Incubation Period of COVID-19 Caused by Unique SARS-CoV-2 Strains: A Systematic Review and Meta-analysis.新型严重急性呼吸综合征冠状病毒 2 株引起的 COVID-19 的潜伏期:系统评价和荟萃分析。
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Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review.COVID-19 感染合并精神障碍患者的谵妄及其他神经精神表现:系统综述。
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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): An Overview.肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)概述
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Delirium and neuropsychological outcomes in critically Ill patients with COVID-19: a cohort study.COVID-19 重症患者的谵妄与神经心理学结局:一项队列研究。
BMJ Open. 2021 Sep 17;11(9):e050045. doi: 10.1136/bmjopen-2021-050045.
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Delirium in Older Patients With COVID-19 Presenting to the Emergency Department.COVID-19 老年患者急诊就诊时出现的谵妄。
JAMA Netw Open. 2020 Nov 2;3(11):e2029540. doi: 10.1001/jamanetworkopen.2020.29540.
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Frequent neurologic manifestations and encephalopathy-associated morbidity in Covid-19 patients.新冠病毒感染患者中频繁出现的神经系统表现和与脑病相关的发病率。
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Delirium in COVID-19: epidemiology and clinical correlations in a large group of patients admitted to an academic hospital.COVID-19 相关性谵妄:在一组入住学术医院的大量患者中的流行病学和临床相关性。
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