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大型腭部溃疡的管理:类天疱疮

Management of a Large Palatal Ulcer: Mucous Membrane Pemphigoid.

作者信息

Badki Simran D, Lohe Vidya, Zamare Vrushali B, Dangore-Khasbage Suwarna, Kadu Ravindra P, Wanjari Mayur B

机构信息

Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2023 Feb 28;15(2):e35619. doi: 10.7759/cureus.35619. eCollection 2023 Feb.

DOI:10.7759/cureus.35619
PMID:37007312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10065370/
Abstract

Mucous membrane pemphigoid (MMP) is an autoimmune disorder that causes inflammatory changes and blistering of the subepithelial layer and is chronic and commonly related to the mucous membranes. It most commonly involves females in the fifth decade of life. In most of the cases, oral mucosa is involved. Dentists might be the first health professional to encounter and make a diagnosis of this rarely occurring disorder with mucocutaneous lesions. This article presents an MMP case report with clinical appearance, diagnosis, management, and follow-up.

摘要

黏膜类天疱疮(MMP)是一种自身免疫性疾病,可导致上皮下层发生炎症变化和水疱形成,病程呈慢性,且通常与黏膜有关。该病最常累及50岁左右的女性。在大多数病例中,口腔黏膜会受到影响。牙医可能是首批接触并诊断这种罕见的伴有皮肤黏膜病变疾病的医疗专业人员。本文介绍了一例黏膜类天疱疮的病例报告,包括临床表现、诊断、治疗及随访情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/c236fe9e0b63/cureus-0015-00000035619-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/9ec0c7070a76/cureus-0015-00000035619-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/26eea07a5dc8/cureus-0015-00000035619-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/c236fe9e0b63/cureus-0015-00000035619-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/9ec0c7070a76/cureus-0015-00000035619-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/26eea07a5dc8/cureus-0015-00000035619-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1009/10065370/c236fe9e0b63/cureus-0015-00000035619-i03.jpg

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1
Management of a Large Palatal Ulcer: Mucous Membrane Pemphigoid.大型腭部溃疡的管理:类天疱疮
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本文引用的文献

1
Oral mucous membrane pemphigoid - Two case reports with varied clinical presentation.口腔黏膜类天疱疮——两例临床表现各异的病例报告。
J Indian Soc Periodontol. 2016 Nov-Dec;20(6):630-634. doi: 10.4103/jisp.jisp_155_16.
2
Urban legend series: mucous membrane pemphigoid.都市传说系列:黏膜类天疱疮
Oral Dis. 2014 Jan;20(1):35-54. doi: 10.1111/odi.12193. Epub 2013 Nov 6.
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Mucous membrane pemphigoid.黏膜类天疱疮
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4
Interleukin-4RA gene polymorphism is associated with oral mucous membrane pemphigoid.白细胞介素-4受体基因多态性与口腔黏膜类天疱疮相关。
Oral Dis. 2014 Apr;20(3):275-80. doi: 10.1111/odi.12106. Epub 2013 Apr 5.
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Pemphigoid diseases.疱疹样疾病。
Lancet. 2013 Jan 26;381(9863):320-32. doi: 10.1016/S0140-6736(12)61140-4. Epub 2012 Dec 11.
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The management of mucous membrane pemphigoid and pemphigus.黏膜类天疱疮和天疱疮的治疗。
Dermatol Ther. 2010 May-Jun;23(3):268-80. doi: 10.1111/j.1529-8019.2010.01323.x.
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Oral mucosal diseases: mucous membrane pemphigoid.口腔黏膜疾病:类天疱疮。
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Mucous membrane pemphigoid: clinical aspects, immunopathological features and therapy.黏膜类天疱疮:临床特征、免疫病理特点及治疗
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Oral pemphigoid autoantibodies preferentially target BP180 ectodomain.
Clin Immunol. 2007 Feb;122(2):207-13. doi: 10.1016/j.clim.2006.10.007. Epub 2006 Dec 1.
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Are rare diseases still orphans or happily adopted? The challenges of developing and using orphan medicinal products.罕见病仍是无人问津的孤儿还是已被欣然接纳?开发和使用孤儿药面临的挑战。
Br J Clin Pharmacol. 2006 Sep;62(3):264-71. doi: 10.1111/j.1365-2125.2006.02654.x.