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病例报告:新型冠状病毒肺炎相关毛霉菌病合并感染:新型冠状病毒肺炎大流行期间首例多重真菌合并感染病例及文献综述

Case report: COVID-19-associated mucormycosis co-infection with : The first case and review on multiple fungal co-infections during COVID-19 pandemic.

作者信息

Erami Mahzad, Mirhendi Hossein, Momen-Heravi Mansooreh, Sharif Alireza, Hashemi Hezaveh Seyed Jamal, Matini Amir Hassan, Ahsaniarani Amir Hossein, Aboutalebian Shima

机构信息

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Department of Infectious Diseases, School of Medicine, Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.

出版信息

Front Med (Lausanne). 2023 Mar 16;10:1078970. doi: 10.3389/fmed.2023.1078970. eCollection 2023.

Abstract

Along with the pandemic COVID-19 spreads, new clinical challenges have emerged in the health care settings, among which there is a high risk of secondary invasive fungal infections with significant mortality. Here, we report a case of invasive fungal rhino orbital sinusitis due to the simultaneous co-infection by and , both identified by sequencing, in a 70-year-old Afghanistanian female with COVID-19. The patient was subjected to surgical debridement as well as taking liposomal amphotericin B, voriconazole, and on discharge, her condition was good. As far as we know, this is the first case of co-infection of COVID-19-associated mucormycosis (CAM) and infection. Multiple fungal co-infections in COVID-19 patients are reviewed.

摘要

随着新型冠状病毒肺炎(COVID-19)大流行的蔓延,医疗环境中出现了新的临床挑战,其中继发性侵袭性真菌感染风险很高,死亡率显著。在此,我们报告一例70岁的阿富汗女性COVID-19患者,因同时感染 和 导致侵袭性真菌性鼻眶窦炎,二者均通过测序鉴定。患者接受了手术清创,并服用了脂质体两性霉素B、伏立康唑,出院时病情良好。据我们所知,这是首例COVID-19相关毛霉病(CAM)和 感染合并感染的病例。本文对COVID-19患者的多种真菌合并感染进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6b5/10061085/6dcaccd44f6c/fmed-10-1078970-g001.jpg

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