一名亚洲女性的晚期中心周围性羟氯喹视网膜病变
Advanced Pericentral Hydroxychloroquine Retinopathy in an Asian Woman.
作者信息
Sheth Neil, Schaab Tara, Mirza Rukhsana G
机构信息
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
出版信息
J Vitreoretin Dis. 2019 Nov 14;4(2):148-151. doi: 10.1177/2474126419885329. eCollection 2020 Mar-Apr.
PURPOSE
This case report describes the unique clinical attributes of pericentral retinopathy associated with hydroxychloroquine (Plaquenil) use in patients of Asian ancestry.
METHODS
A complete ophthalmologic examination including optical coherence tomography, fundus autofluorescence, and Humphrey visual fields was performed. Serial images were obtained at subsequent follow-up appointments.
RESULTS
A dilated fundus examination demonstrated extensive bilateral parafoveal and perifoveal atrophy extending past the superior and inferior arcades as well as central macular preservation. Fundus autofluorescence exhibited prominent pericentral hypoautofluorescence.
CONCLUSIONS
The distinct variant of pericentral hydroxychloroquine retinopathy has become increasingly recognized in patients of Asian origin. It is important for ophthalmologists to distinguish this pattern and consider modifying screening methods.
目的
本病例报告描述了亚洲裔患者使用羟氯喹（羟氯喹片）相关的中心周视网膜病变的独特临床特征。
方法
进行了包括光学相干断层扫描、眼底自发荧光和汉弗莱视野检查在内的全面眼科检查。在后续随访预约时获取了系列图像。
结果
散瞳眼底检查显示广泛的双侧黄斑旁和黄斑周萎缩，延伸至上下血管弓之外，以及中心黄斑保留。眼底自发荧光显示中心周明显低自发荧光。
结论
中心周羟氯喹视网膜病变的独特变体在亚洲裔患者中越来越受到认可。眼科医生区分这种模式并考虑修改筛查方法很重要。
Zotero 插件