报告 犬钩虫 一种在加拿大对抗寄生虫药物产生抗药性的新威胁。
Compte rendu The canine hookworm A novel threat for anthelmintic resistance in Canada.
机构信息
Faculté de médecine vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Nezami, Godoy); Hôpital vétérinaire de Buckingham, 606 Avenue de Buckingham, Gatineau, Québec J8L 2H5 (Blanchard).
出版信息
Can Vet J. 2023 Apr;64(4):372-378.
Abstract
The canine hookworm is one of the most prevalent parasitic nematodes in dogs worldwide and has the potential for zoonotic transmission to humans, including the development of cutaneous larva migrans. Recent confirmation of anthelmintic resistance (AR) in to several anthelmintic classes, mainly in the USA, indicates the potential for this scenario in Canada. We consider various factors that may lead to resistant isolates in Canada, such as the widespread use of antiparasitic drugs without the assessment of efficacy; increased prevalence in various Canadian provinces; and the importation of dogs, mostly from the USA, with a history of persistent infection by . Our objective was to review factors that influence to develop AR and raise awareness regarding the need for a strategic plan to control this parasitic nematode through the appropriate use of anthelmintics.
摘要
犬钩虫是全球犬类最普遍的寄生性线虫之一，具有向人类传播的潜在可能性，包括皮肤幼虫移行症的发生。最近在美国等地确认了几种驱虫药物的驱虫耐药性 (AR)，这表明加拿大也可能存在这种情况。我们考虑了可能导致加拿大出现耐药分离株的各种因素，例如在没有评估疗效的情况下广泛使用驱虫药物；在加拿大不同省份的 prevalence 增加；以及从美国进口的犬类数量增加，这些犬类大多有持续感染 的历史。我们的目的是综述影响 产生 AR 的因素，并提高人们对通过适当使用驱虫药物来控制这种寄生线虫的战略计划的必要性的认识。
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