Suppr超能文献

及时的手术固定可为伴有轻度至中度创伤性脑损伤的连枷胸患者带来有益的结果:一项创伤质量改进项目分析-一项队列研究。

Timely surgical fixation confers beneficial outcomes in patients' concomitant flail chest with mild-to-moderate traumatic brain injury: a trauma quality improvement project analysis - a cohort study.

机构信息

Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei.

Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University, Taoyuan, Taiwan, Republic of China.

出版信息

Int J Surg. 2023 Apr 1;109(4):729-736. doi: 10.1097/JS9.0000000000000271.

Abstract

BACKGROUND

Traumatic flail chest results in respiratory distress and prolonged hospital stay. Timely surgical fixation of the flail chest reduces respiratory complications, decreases ventilator dependence, and shortens hospital stays. Concomitant head injury is not unusual in these patients and can postpone surgical timing due to the need to monitor the status of intracranial injuries. Reducing pulmonary sequelae also assists in the recovery from traumatic brain injury and improves outcomes. No previous evidence supports that early rib fixation can improve the outcome of patients with concomitant flail chest and traumatic brain injury.

RESEARCH QUESTION

Can early rib fixation improve the outcome of patients with concomitant flail chest and traumatic brain injury?

STUDY DESIGN AND METHODS

Adult patients with blunt injuries from the Trauma Quality Improvement Project between 2017 and 2019 were eligible for inclusion. Patients were divided into two treatment groups: operative and nonoperative. Inverse probability treatment weighting was used to identify the predictors of mortality and adverse hospital events.

RESULTS

Patients in the operative group had a higher intubation rate [odds ratio (OR), 2.336; 95% CI, 1.644-3.318; p <0.001), a longer length of stay (coefficient β , 4.664; SE, 0.789; p <0.001), longer ventilator days (coefficient β , 2.020; SE, 0.528; p <0.001), and lower mortality rate (OR], 0.247; 95% CI, 0.135-0.454; p <0.001).

INTERPRETATION

Timely rib fixation can improve the mortality rate of patients with flail chest and a concomitant mild-to-moderate head injury.

摘要

背景

创伤性连枷胸导致呼吸窘迫和住院时间延长。及时对连枷胸进行手术固定可减少呼吸并发症,降低对呼吸机的依赖,并缩短住院时间。此类患者常合并颅脑损伤,需要监测颅内损伤情况,因此手术时机可能会延迟。减少肺部后遗症也有助于创伤性脑损伤的恢复并改善预后。目前尚无证据表明早期肋骨固定可以改善合并连枷胸和创伤性脑损伤患者的预后。

研究问题

早期肋骨固定能否改善合并连枷胸和创伤性脑损伤患者的预后?

研究设计和方法

从 2017 年至 2019 年的创伤质量改进计划中筛选出符合条件的成年钝性损伤患者。患者分为手术组和非手术组。采用逆概率治疗加权法识别死亡率和不良住院事件的预测因素。

结果

手术组患者的插管率更高[比值比(OR),2.336;95%置信区间(CI),1.644-3.318;p<0.001),住院时间更长(系数β,4.664;SE,0.789;p<0.001),呼吸机使用时间更长(系数β,2.020;SE,0.528;p<0.001),死亡率更低(OR,0.247;95%CI,0.135-0.454;p<0.001)。

结论

及时进行肋骨固定可以降低合并轻度至中度颅脑损伤的连枷胸患者的死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a24/10389630/a82149e18ed5/js9-109-0729-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验