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伪装成周围神经鞘瘤的上腰椎远外侧椎间盘突出症:病例说明

Upper lumbar spine far lateral disc herniations masquerading as peripheral nerve sheath tumors: illustrative cases.

作者信息

Uy Benjamin R, Sun Matthew Z, Muftuoglu Yagmur, Cheng Megan, Kim Wi Jin, Magaki Shino, Yoo Brian Y, Salehi Banafsheh, Beckett Joel S, Macyszyn Luke

出版信息

J Neurosurg Case Lessons. 2023 Apr 3;5(14). doi: 10.3171/CASE22552.

Abstract

BACKGROUND

Migratory disc herniations can mimic neoplasms clinically and on imaging. Far lateral lumbar disc herniations usually compress the exiting nerve root and can be challenging to distinguish from a nerve sheath tumor due to the proximity of the nerve and characteristics on magnetic resonance imaging (MRI). These lesions can occasionally present in the upper lumbar spine region at the L1-2 and L2-3 levels.

OBSERVATIONS

The authors describe 2 extraforaminal lesions in the far lateral space at the L1-2 and L2-3 levels, respectively. On MRI, both lesions tracked along the corresponding exiting nerve roots with avid postcontrast rim enhancement and edema in the adjacent muscle tissue. Thus, they were initially concerning for peripheral nerve sheath tumors. One patient underwent fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) screening and demonstrated moderate FDG uptake on PET-CT scan. In both cases, intraoperative and postoperative pathology revealed fibrocartilage disc fragments.

LESSONS

Differential diagnosis for lumbar far lateral lesions that are peripherally enhancing on MRI should include migratory disc herniation, regardless of the level of the disc herniations. Accurate preoperative diagnosis can aid in decision making for management, surgical approach, and resection.

摘要

背景

迁移性椎间盘突出在临床和影像学上可类似肿瘤。腰椎极外侧椎间盘突出通常压迫出口神经根,由于神经的毗邻关系及磁共振成像(MRI)特征,与神经鞘瘤鉴别具有挑战性。这些病变偶尔可出现在上腰椎区域的L1 - 2和L2 - 3节段。

观察结果

作者分别描述了2例位于L1 - 2和L2 - 3节段极外侧间隙的椎间孔外病变。在MRI上,两个病变均沿相应的出口神经根走行,增强扫描后边缘强化明显,相邻肌肉组织有水肿。因此,最初怀疑为周围神经鞘瘤。1例患者接受了氟脱氧葡萄糖正电子发射断层扫描 - 计算机断层扫描(FDG PET - CT)筛查,PET - CT扫描显示FDG摄取中等。两例患者术中及术后病理均显示为纤维软骨椎间盘碎片。

经验教训

对于MRI上周边强化的腰椎极外侧病变,鉴别诊断应包括迁移性椎间盘突出,无论椎间盘突出的节段如何。准确的术前诊断有助于管理、手术入路和切除的决策制定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/754e/10555549/56a4a44419dd/CASE22552f1.jpg

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