Peter Boris Centre for Addiction Research, McMaster University & St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.
Homewood Research Institute, Guelph, Ontario, Canada.
J Stud Alcohol Drugs. 2023 Jul;84(4):570-578. doi: 10.15288/jsad.22-00212. Epub 2023 Mar 30.
Impulsivity is a multidimensional construct consistently associated with problematic substance use, but less is known about its relevance to clinical outcomes. The current study examined whether impulsivity changed over the course of addiction treatment and whether the changes were associated with changes in other clinical outcomes.
Participants were patients in a large inpatient addiction medicine program ( = 817; 71.40% male). Impulsivity was assessed using a self-report measure of delay discounting (i.e., overvaluation of smaller immediate rewards) and the UPPS-P Impulsive Behavior Scale, a self-report measure of impulsive personality traits. Outcomes were psychiatric symptoms including depression, anxiety, posttraumatic stress disorder, and drug cravings.
Within-subjects analyses of variance revealed significant within-treatment changes in all UPPS-P subscales, all psychiatric indicators, and craving ( < .005), but not delay discounting. Changes in all UPPS-P traits, except for sensation seeking, were significantly positively associated with changes in psychiatric symptoms and cravings over the course of treatment ( < .01).
These findings reveal that facets of impulsive personality change across addiction treatment and are generally related to positive changes in other clinically relevant outcomes. Evidence of change despite no explicit intervention targeting suggests that impulsive personality traits may be viable treatment targets in substance use disorder treatment.
冲动是一个与问题物质使用密切相关的多维结构,但关于其与临床结果的相关性知之甚少。本研究考察了冲动是否会在成瘾治疗过程中发生变化,以及这种变化是否与其他临床结果的变化相关。
参与者为大型住院成瘾医学项目的患者(n=817;71.40%为男性)。使用延迟折扣自我报告量表(即对较小即时奖励的高估)和 UPPS-P 冲动行为量表评估冲动性,这是一种冲动人格特质的自我报告量表。结果是包括抑郁、焦虑、创伤后应激障碍和药物渴求在内的精神症状。
方差的受试者内分析显示,所有 UPPS-P 分量表、所有精神指标和渴求(<0.005)在治疗过程中均发生了显著的治疗内变化,但延迟折扣没有变化。除感觉寻求外,UPPS-P 特质的所有变化都与治疗过程中精神症状和渴求的变化呈显著正相关(<0.01)。
这些发现表明,冲动人格特质在成瘾治疗过程中会发生变化,并且通常与其他临床相关结果的积极变化相关。尽管没有针对特定目标的明确干预措施,但仍存在变化的证据表明,冲动人格特质可能是物质使用障碍治疗中的可行治疗目标。