Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, USA.
Kessler Foundation, West Orange, NJ, USA.
Spinal Cord. 2023 Nov;61(11):579-586. doi: 10.1038/s41393-023-00894-2. Epub 2023 Apr 5.
Central cord syndrome (CCS) is the most common, yet most controversial, among the different spinal cord injury (SCI) incomplete syndromes. Since its original description in 1954, many variations have been described while maintaining the core characteristic of disproportionate weakness in the upper extremities compared to the lower extremities. Several definitions have been proposed in an attempt to quantify this difference, including a widely accepted criterion of ≥10 motor points in favor of the lower extremities. Nevertheless, recent reports have recommended revisiting the terminology and criteria of CCS as existing definitions do not capture the entire essence of the syndrome. Due to methodological differences, the full extent of CCS is not known, and a large variation in prevalence has been described. This review classifies the different definitions of CCS and describes some inherent limitations, highlighting the need for universal quantifiable criteria.
中央脊髓综合征（CCS）是不同脊髓损伤（SCI）不完全综合征中最常见但也是最具争议的一种。自 1954 年首次描述以来，尽管保持了上肢相对于下肢的不成比例的无力这一核心特征，但已经描述了许多变体。为了量化这种差异，已经提出了几种定义，包括一个广泛接受的标准，即有利于下肢的运动点≥10 个。然而，最近的报告建议重新审视 CCS 的术语和标准，因为现有的定义并没有捕捉到该综合征的全部本质。由于方法学上的差异，CCS 的全貌尚不清楚，其患病率也存在很大差异。本综述对 CCS 的不同定义进行了分类，并描述了一些内在的局限性，强调了需要制定通用的可量化标准。
