The George Institute for Global Health.
Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University.
J Hypertens. 2023 Jun 1;41(6):1003-1010. doi: 10.1097/HJH.0000000000003428. Epub 2023 Apr 3.
Cuffless wearable blood pressure (BP) devices may allow detailed evaluation of BP for prolonged periods, but their ability to accurately track BP changes is uncertain. We investigated whether a commercially available cuffless wearable device tracks: 24-h systolic (SBP) and diastolic BP (DBP) compared to conventional ambulatory monitoring (ABPM); and antihypertensive medication-induced BP changes compared to cuff-based home BP monitoring (HBPM).
We fitted 41 participants (32% females, 58 ± 14 years, 80% hypertensive) with a wrist-wearable cuffless BP device (Aktiia) continuously for 6-12 days. At the beginning and the end of this period, 24-h ABPM was performed. Three participants with hypertension (one female; 60 ± 8 years) wore the Aktiia device and performed HBPM continuously one week before and 2 weeks after antihypertensive medication uptitration.
Compared to ABPM, Aktiia reported higher average SBP for 24-h (difference 4.9 mmHg, 95% CI [1.9, 7.9]) and night-time (15.5[11.8, 19.1] mmHg; all P ≤ 0.01), but similar daytime (1.0 [-1.8, 3.8] mmHg; P = 0.48). Similarly, average cuffless DBP was higher for 24-h (4.2 [2.3, 6.0] mmHg) and night-time (11.8 [9.5, 14.1] mmHg; both P < 0.001), but similar during daytime (1.4 [-0.4, 3.23] mmHg; P = 0.13). Aktiia also reported reduced night-time dip for SBP (difference 14.2 [12.1, 16.3] mmHg) and DBP (10.2 [8.5, 11.9] mmHg; both P < 0.001). The average medication-induced SBP/DBP decline after 2 weeks of uptitration was -1.0/-0.8 mmHg with Aktiia vs. -19.7/-11.5 mmHg with HBPM ( P = 0.03 for difference).
This cuffless wearable device did not accurately track night-time BP decline and results suggested it was unable to track medication-induced BP changes.
无袖带可穿戴血压（BP）设备可以长时间详细评估血压，但尚不确定其是否能准确跟踪血压变化。我们研究了一种市售的无袖带可穿戴设备是否能：与传统的动态血压监测（ABPM）相比，跟踪 24 小时收缩压（SBP）和舒张压（DBP）；与基于袖带的家庭血压监测（HBPM）相比，跟踪降压药物引起的血压变化。
我们连续 6-12 天为 41 名参与者（32%为女性，58±14 岁，80%为高血压患者）佩戴腕部无袖带 BP 设备（Aktiia）。在此期间的开始和结束时，进行 24 小时 ABPM。3 名高血压患者（1 名女性；60±8 岁）连续佩戴 Aktiia 设备，并在降压药物滴定前一周和后两周进行 HBPM。
与 ABPM 相比，Aktiia 报告的 24 小时平均 SBP 更高（差值为 4.9mmHg，95%CI[1.9，7.9]）和夜间（15.5[11.8，19.1]mmHg；均 P≤0.01），但日间相似（1.0[-1.8，3.8]mmHg；P=0.48）。同样，平均无袖带 DBP 24 小时更高（4.2[2.3，6.0]mmHg）和夜间（11.8[9.5，14.1]mmHg；均 P＜0.001），但日间相似（1.4[-0.4，3.23]mmHg；P=0.13）。Aktiia 还报告夜间 SBP 下降幅度减少（差值 14.2[12.1，16.3]mmHg）和 DBP（10.2[8.5，11.9]mmHg；均 P＜0.001）。经过 2 周的滴定后，平均药物诱导的 SBP/DBP 下降值分别为 Aktiia 组的-1.0/-0.8mmHg 和 HBPM 组的-19.7/-11.5mmHg（差值 P=0.03）。
这种无袖带可穿戴设备不能准确跟踪夜间血压下降，结果表明其无法跟踪药物引起的血压变化。
