Department of Paediatric Dentistry and Behavioural Science, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
Eur J Oral Sci. 2023 Jun;131(3):e12930. doi: 10.1111/eos.12930. Epub 2023 Apr 6.
This study investigated the prevalence and associations of molar-incisor hypomineralisation (MIH) in 8-9 year-old children in Oslo. A total of 3013 children in one age cohort participated in the study during their regular dental examination at the Public Dental Service. Hypomineralised enamel defects were recorded according to the European Academy of Paediatric Dentistry criteria for MIH. Information on health and medications used during pregnancy and in the child's first 3 years of life was obtained from a questionnaire administered to parents. The overall prevalence of MIH was 28.2%, with no gender difference. A higher prevalence of MIH was found in children who had been ill or had used medication in early life and in those whose mother had been ill during pregnancy. No association was found between MIH and prematurity or maternal use of medication during pregnancy. The multivariable analyses showed that children with MIH were more likely to have suffered from illness in early life (OR = 1.41, 95% CI: 1.17-1.70), used antibiotics during the first year of life (OR = 1.68, 95% CI: 1.19-2.35), experienced tooth pain (OR = 1.33, 95% CI: 1.03-1.72), and experienced pain while toothbrushing (OR = 2.17, 95% CI: 1.46-3.23) than children without MIH. The prevalence of MIH was high in the children participating in this study.
本研究调查了奥斯陆 8-9 岁儿童中磨牙-切牙釉质发育不全(MIH)的流行情况及其相关性。在公共牙科服务的常规牙科检查中,共有 3013 名同一年龄组的儿童参与了这项研究。根据欧洲儿童牙科学会(EAPD)制定的 MIH 标准,记录了矿化不全的釉质缺陷。通过向家长发放问卷,获取了有关儿童在怀孕期间和生命最初 3 年中健康状况和使用药物的信息。MIH 的总体患病率为 28.2%,无性别差异。在生命早期生病或使用药物以及母亲在怀孕期间生病的儿童中,MIH 的患病率较高。MIH 与早产或母亲在怀孕期间使用药物之间没有关联。多变量分析表明,患有 MIH 的儿童在生命早期更有可能生病(OR=1.41,95%CI:1.17-1.70),在生命的第一年使用抗生素(OR=1.68,95%CI:1.19-2.35),经历过牙痛(OR=1.33,95%CI:1.03-1.72),以及在刷牙时感到疼痛(OR=2.17,95%CI:1.46-3.23),而没有 MIH 的儿童。本研究中参与研究的儿童 MIH 患病率较高。