Arce Nestor, Boonnak Kobporn, Bernasor Lee Thunder, Salas Christian Joy, Putri Anastasia, Aung Pyae Linn, Imad Hisham Ahmed, Chierakul Wirongrong, Luvira Viravarn, Phonrat Benjaluck, Phumratanaprapin Weerapong, Charunwatthana Prakaykaew
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Jose Maria College Foundation, Inc., College of Medicine, Davao City 8000, Philippines.
Reports (MDPI). 2024 Dec 11;7(4):112. doi: 10.3390/reports7040112.
Mosquito-borne diseases such as dengue and chikungunya are endemic to tropical regions and are common causes of acute febrile illness in both adults and children. The Philippines, home to more than one hundred million residents and visited by several million tourists each year, is one such region where the risk of these diseases is endemic. To better understand the detailed situation, we estimated the proportion of these diseases in the community by conducting a prospective observational study in four provincial hospitals of Davao de Oro, Philippines, from February 2019 to February 2020. Sera from 382 study participants were used for laboratory confirmation of dengue or chikungunya by serology. Dengue was diagnosed in 57.1%, chikungunya in 7.07%, and coinfection with both dengue and chikungunya in 7.3%, while the etiology was undetermined in 35.9% of the study participants. Common clinical symptoms included fever, headache, and a rash, which were overlapping symptoms that were clinically indistinguishable at the presentation to the hospital, necessitating laboratory diagnostics. The identification of the presence of chikungunya in Davao de Oro calls for increased awareness, improved diagnostics, and integrated disease control measures to manage outbreaks that can occur in dengue-endemic regions.
登革热和基孔肯雅热等蚊媒疾病在热带地区流行，是成人和儿童急性发热性疾病的常见病因。菲律宾有超过一亿居民，每年有几百万游客到访，是这些疾病风险流行的地区之一。为了更好地了解详细情况，我们于2019年2月至2020年2月在菲律宾北达沃省的四家省级医院进行了一项前瞻性观察研究，以估计这些疾病在社区中的比例。382名研究参与者的血清用于通过血清学对登革热或基孔肯雅热进行实验室确诊。登革热确诊率为57.1%，基孔肯雅热为7.07%，登革热和基孔肯雅热合并感染为7.3%，而35.9%的研究参与者病因未明。常见临床症状包括发热、头痛和皮疹，这些是重叠症状，在就诊时临床上无法区分，需要实验室诊断。在北达沃省发现基孔肯雅热病例，这就需要提高认识、改进诊断方法，并采取综合疾病控制措施来管理登革热流行地区可能发生的疫情。
