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剖析经导管渐缩动脉中纳米金刚石和二氧化硅的本质:亲水特性解析。

Unraveling the nature of nano-diamonds and silica in a catheterized tapered artery: highlights into hydrophilic traits.

机构信息

Basic Science, Faculty of Engineering, The British University in Egypt, Al-Shorouk City, Cairo, 11837, Egypt.

College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao, 266590, Shandong, China.

出版信息

Sci Rep. 2023 Apr 7;13(1):5684. doi: 10.1038/s41598-023-32604-6.

Abstract

In this work, we observe the behavior of a hybrid nanofluidic model containing nanodiamonds and silica nanoparticles. The nanofluid propagates through a catheterized tapered artery with three distinct configurations: converging tapered, non-tapered and diverging tapered arteries. In order to assess the rheological properties of the blood, the third-grade non-Newtonian fluid is employed in the flow model such that the Newtonian versus non-Newtonian effects are revealed. The system of equations governing the flow is modeled under magnetic field and with heat transfer, then solved in a closed form using the perturbation approach for the pertinent parameters. The interpretations of the physical variables of interest, such as the velocity, temperature and wall shear stress, are explained. The integration of diamonds and silica nanoparticles give rise to diverse of biological applications since they are used in the drug delivery and biological imaging in genetic materials due to their hydrophilic surfaces. The present mathematical analysis lays a solid foundation on possible therapeutic applications in biomedicine.

摘要

在这项工作中,我们观察了含有纳米金刚石和二氧化硅纳米粒子的混合纳流型的行为。纳流通过具有三个不同构型的导管化锥形动脉传播:收敛锥形、非锥形和发散锥形动脉。为了评估血液的流变性质,在流动模型中采用了三阶非牛顿流体,从而揭示了牛顿与非牛顿效应。在磁场和传热的作用下对控制流动的方程组进行建模,然后使用摄动方法对相关参数进行封闭形式求解。解释了感兴趣的物理变量,如速度、温度和壁面剪切应力。钻石和二氧化硅纳米粒子的结合由于其亲水表面,因此在药物输送和遗传物质的生物成像中被用于多种生物应用。本数学分析为生物医学中的可能治疗应用奠定了坚实的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a3/10082197/37a77107a805/41598_2023_32604_Fig1_HTML.jpg

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