新生儿缺氧缺血性脑病临床实践指南：使用研究与评价指南评估（AGREE）II工具进行的系统评价
Clinical practice guidelines for neonatal hypoxic-ischemic encephalopathy: A systematic review using the appraisal of guidelines for research and evaluation (AGREE) II instrument.
作者信息
Amer Yasser S, Anabrees Jasim, Abdelmawla Mohamed, Abdalgader Ayman, Almazroei Asmaa, Alhifzi Ibrahim, AlOnazi Abdullah Hawash, Sabr Yasser, Hneiny Layal, El-Malky Ahmed, Alshalawi Ayesha, Alayoubi Ahmed, Chaudhry Iftikhar A, Elkhateeb Omar
机构信息
Pediatrics Department, King Khalid University Hospital, King Saud University Medical City, Riyadh, Saudi Arabia.
Clinical Practice Guidelines and Quality Research Unit, Quality Management Department, King Saud University Medical City, Riyadh, Saudi Arabia.
出版信息
Front Pediatr. 2023 Mar 22;11:1092578. doi: 10.3389/fped.2023.1092578. eCollection 2023.
BACKGROUND AND OBJECTIVE
To systematically review, critically appraise the quality of recent clinical practice guidelines (CPGs) for neonatal hypoxic ischemic encephalopathy (HIE), and map their recommendations.
DATA SOURCES
CPG databases (GIN, ECRI, NICE, SIGN, DynaMed), Bibliographic databases (PubMed, Embase, CINAHL), and related specialized professional societies (e.g., AAP, CPS, BAPM, RCPCH, and SNS).
STUDY SELECTION
Original de-novo developed evidence-based CPGs for HIE, group authorship, Arabic or English languages, and international or national scope. The systematic review was drafted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement and Johnston et al methodological guide.
DATA EXTRACTION
Quality assessment of the included HIE CPGs by the Appraisal of Guidelines for REsearch & Evaluation II (AGREE II) Instrument and report their characteristics, AGREE II ratings, and recommendations.
DATA SYNTHESIS
Our search retrieved 2,489 citations, of which two recent HIE CPGs were eligible and appraised: Canadian Paediatric Society (CPS) and Queensland Maternity and Neonatal Services (QMN). The overall assessment of the QMN CPG was superior (83%). Domain 1 (Scope & Purpose) scored (47%, 63%), Domain 2 (Stakeholder Involvement) (72%, 39%), Domain 3 (Rigour of Development) (48%, 43%), Domain 4 (Clarity & Presentation) (100%, 96%), Domain 5 (Applicability) (59%, 9%), and Domain 6 (Editorial Independence) (67%, 17%) for the QMN and CPS CPGs respectively. All appraisers recommended the QMN CPG for use in practice.
CONCLUSION
The methodological quality of the QMN CPG was superior with the relevant recommendations for its use in neonatal practice.
LIMITATIONS
limited to Arabic and English languages.
SYSTEMATIC REVIEW REGISTRATION
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258291, identifier: CRD42021258291.
背景与目的
系统回顾并严格评估近期新生儿缺氧缺血性脑病（HIE）临床实践指南（CPG）的质量，并梳理其推荐意见。
数据来源
CPG数据库（GIN、ECRI、NICE、SIGN、DynaMed）、文献数据库（PubMed、Embase、CINAHL）以及相关专业学会（如美国儿科学会、加拿大儿科学会、英国小儿麻醉医师协会、英国皇家儿科学会与儿童健康学院、苏格兰新生儿学会）。
研究选择
针对HIE全新制定的基于证据的原创CPG，集体作者身份，阿拉伯语或英语，国际或国家范围。系统评价依据系统评价与Meta分析的首选报告项目（PRISMA）声明及约翰斯顿等人的方法学指南起草。
数据提取
采用《研究与评价指南评估II》（AGREE II）工具对纳入的HIE CPG进行质量评估，并报告其特征、AGREE II评分及推荐意见。
数据综合
我们的检索共获得2489条引文，其中有两份近期的HIE CPG符合纳入标准并进行了评估：加拿大儿科学会（CPS）和昆士兰母婴服务机构（QMN）。QMN CPG的总体评估结果更优（83%）。QMN和CPS CPG在领域1（范围与目的）的得分分别为（47%，63%），领域2（利益相关者参与）（72%，39%），领域3（制定的严谨性）（48%，43%），领域4（清晰性与呈现）（100%，96%），领域5（适用性）（59%，9%），领域6（编辑独立性）（67%，17%）。所有评估者均推荐在实践中使用QMN CPG。
结论
QMN CPG的方法学质量更优，且有相关建议可用于新生儿实践。
局限性
限于阿拉伯语和英语。
系统评价注册
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258291，标识符：CRD42021258291。
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