Poultry Institute, Shandong Academy of Agricultural Sciences, Jinan, 250100, China.
College of Life Sciences, Shandong Normal University, Jinan, 250014, China.
Braz J Microbiol. 2023 Jun;54(2):1309-1314. doi: 10.1007/s42770-023-00963-x. Epub 2023 Apr 10.
Sapporo virus (SaV) is an emerging enteric virus causing acute gastroenteritis in animals. Here, we found a novel porcine SaV (PoSaV) strain (named SD2202) from the piglets with diarrhea in China in 2022. The highest nucleotide homology of SD2202 with other PoSaV strains is only 90.67%, and there are four amino acids insertion in the viral capsid protein and minor structural protein compared to other PoSaV; furthermore, we found that SD2202 belongs to a new GIII genogroup clade (GIII-6 clade). Interestingly, we found that SD2202 may be an intra-genogroup recombinant strain. Taken together, we found a novel PoSaV implicated in the piglet diarrhea epidemic and emphasized the importance of continuous surveillance of PoSaV.
札幌病毒（SaV）是一种新兴的肠道病毒，可导致动物发生急性胃肠炎。在这里，我们从 2022 年中国腹泻仔猪中发现了一种新型猪 SaV（PoSaV）株（命名为 SD2202）。与其他 PoSaV 株相比，SD2202 与其他 PoSaV 株的核苷酸同源性最高仅为 90.67%，病毒衣壳蛋白和次要结构蛋白中有 4 个氨基酸插入；此外，我们发现 SD2202 属于一个新的 GIII 基因组群分支（GIII-6 分支）。有趣的是，我们发现 SD2202 可能是一个属内重组株。总之，我们发现了一种与仔猪腹泻流行有关的新型 PoSaV，并强调了持续监测 PoSaV 的重要性。
