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自体黑素细胞-角质形成细胞移植及窄谱中波紫外线治疗后面部瘢痕显著加重:一例报告

Notable Enhancement of Facial Scarring Following Autologous Melanocyte-Keratinocyte Transplantation and NUVB Therapy: A Case Report.

作者信息

Nilforoushzadeh Mohammad Ali, Nouri Maryam, Alavi Shiva, Amirkhani Mohammad Amir, Zare Solmaz, Alavi Rad Ehsan, Roohaninasab Masoumeh, Behrangi Elham, Shamloo Amir, Maleki Bahareh, Zare Sona

机构信息

Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Skin Repair Research Center, Jordan Dermatology and Hair Transplantation Center, Tehran, Iran.

出版信息

J Lasers Med Sci. 2022 Dec 28;13:e78. doi: 10.34172/jlms.2022.78. eCollection 2022.

Abstract

There are various types of treatment targeting healing traumatic or accidental skin scars. Transplantation of skin grafts and surgical alternatives, including autologous transplantation of melanocyte-keratinocyte suspension, have also been suggested previously. This study is representing a case of previous skin graft transplantation, complaining of scar formation and discoloration on the transplanted segment. The patient was a 37-year-old lady. This patient underwent melanocyte-keratinocyte suspension transplantation and narrow-band ultraviolet B (NUVB) therapy and could reach 40% re-pigmentation enhancement. This method could be introduced as an efficient and safe method of approaching facial scarring. This method could be introduced as an efficient and safe method of approaching facial scarring.

摘要

有多种针对愈合创伤性或意外性皮肤瘢痕的治疗方法。先前也有人提出皮肤移植和手术替代方案,包括黑素细胞 - 角质形成细胞悬液自体移植。本研究报告了一例既往皮肤移植病例,患者主诉移植部位出现瘢痕形成和色素沉着。患者为一名37岁女性。该患者接受了黑素细胞 - 角质形成细胞悬液移植和窄谱中波紫外线(NUVB)治疗,色素再沉着增强可达40%。该方法可作为一种有效且安全的治疗面部瘢痕的方法。该方法可作为一种有效且安全的治疗面部瘢痕的方法。

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A study of autologous melanocyte transfer in treatment of stable vitiligo.自体黑素细胞移植治疗稳定期白癜风的研究
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本文引用的文献

1
Management of Facial Scars.面部瘢痕的管理
Facial Plast Surg. 2019 Dec;35(6):666-671. doi: 10.1055/s-0039-3401642. Epub 2019 Nov 29.
2
Facial Scar Improvement Procedures.面部瘢痕改善手术。
Facial Plast Surg. 2018 Oct;34(5):448-457. doi: 10.1055/s-0038-1669400. Epub 2018 Oct 8.
8
Melanocyte transplant in piebaldism: case report.
An Bras Dermatol. 2010 May-Jun;85(3):384-8. doi: 10.1590/s0365-05962010000300016.
9
Dermatosurgical techniques for repigmentation of vitiligo.用于白癜风色素再生的皮肤外科技术。
Int J Dermatol. 2006 Apr;45(4):411-7. doi: 10.1111/j.1365-4632.2006.02486.x.

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