犬发作性睡病中猝倒相关的心率和血压变化。
Heart rate and blood pressure changes associated with cataplexy in canine narcolepsy.
作者信息
Siegel J M, Fahringer H, Tomaszewski K S, Kaitin K, Kilduff T, Dement W C
出版信息
Sleep. 1986;9(1 Pt 2):216-21. doi: 10.1093/sleep/9.1.216.
Abstract
Blood pressure and heart rate were monitored in narcoleptic dogs by means of a chronically implanted catheter placed in the descending aorta. Changes in these variables were recorded during spontaneously occurring cataplectic episodes. We found no reliable change in blood pressure associated with cataplexy onset. However, heart rate showed a marked increase prior to the onset of cataplexy, with peak heart rates being reached at or shortly after the disappearance of muscle tone. Autonomic events correlated with increased heart rate may contribute to the triggering of cataplexy in narcoleptics.
摘要
通过长期植入降主动脉的导管对发作性睡病犬的血压和心率进行监测。在自然发生的猝倒发作期间记录这些变量的变化。我们发现与猝倒发作开始相关的血压没有可靠变化。然而，心率在猝倒发作前显著增加，在肌张力消失时或消失后不久达到心率峰值。与心率增加相关的自主神经事件可能有助于触发发作性睡病患者的猝倒。
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