Instituto Nacional de Investigación Agropecuaria, Plataforma de Salud Animal, Estación Experimental del Norte, Tacuarembó, Uruguay.
Polo de Desarrollo Universitario Del Instituto Superior de La Carne, Centro Universitario Regional (CENUR) Noreste, Universidad de La República, Tacuarembó, Uruguay.
Toxicon. 2023 Jun 15;229:107124. doi: 10.1016/j.toxicon.2023.107124. Epub 2023 Apr 11.
An outbreak of poisoning by Lantana camara occurred in cattle when a herd sought refuge in a Eucalyptus forest heavily infested by this plant. The animals showed apathy, elevated serum activities of hepatic enzymes, severe photosensitivity, jaundice, hepatomegaly and nephrosis. After a clinical manifestation period of 2-15 days, 74 out of 170 heifers died. The main histological changes were random hepatocellular necrosis, cholestasis, biliary proliferation and, in one animal, centrilobular necrosis. Immunostaining for Caspase 3 detected scattered apoptotic hepatocytes.
当一群牛躲在被该植物严重寄生的桉树森林中时,发生了一场马缨丹中毒事件。这些动物表现出冷漠、血清肝酶活性升高、严重的光敏感性、黄疸、肝肿大和肾病。在 2-15 天的临床表现期后,170 头小母牛中有 74 头死亡。主要的组织学变化是随机的肝细胞坏死、胆汁淤积、胆管增生,并且在一只动物中出现了中央小叶坏死。Caspase 3 的免疫染色检测到散在的凋亡肝细胞。