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新冠后间质性肺病——冰山一角。

Post-COVID Interstitial Lung Disease-The Tip of the Iceberg.

机构信息

Department for BioMedical Research DBMR, Inselspital, Bern University Hospital, University of Bern, Switzerland; Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Department of Respiratory Medicine, Antrim Area Hospital, Northern Health and Social Care Trust, Antrim, Northern Ireland, UK.

出版信息

Immunol Allergy Clin North Am. 2023 May;43(2):389-410. doi: 10.1016/j.iac.2023.01.004. Epub 2023 Mar 3.

DOI:10.1016/j.iac.2023.01.004
PMID:37055095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9982726/
Abstract

The proportion of symptomatic patients with post-coronavirus 2019 (COVID-19) condition (long COVID) represents a significant burden on the individual as well as on the health care systems. A greater understanding of the natural evolution of symptoms over a longer period and the impacts of interventions will improve our understanding of the long-term impacts of the COVID-19 disease. This review will discuss the emerging evidence for the development of post-COVID interstitial lung disease focusing on the pathophysiological mechanisms, incidence, diagnosis, and impact of this potentially new and emerging respiratory disease.

摘要

新冠病毒 2019 后症状患者(长新冠)的比例对个人和医疗保健系统来说都是一个重大负担。对症状在更长时间内的自然演变和干预措施的影响有更深入的了解,将提高我们对 COVID-19 疾病长期影响的认识。本综述将讨论新冠后间质性肺病的新出现证据,重点关注潜在的新出现呼吸道疾病的病理生理机制、发病率、诊断和影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e08/9982726/daac4a8e373d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e08/9982726/daac4a8e373d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e08/9982726/daac4a8e373d/gr1_lrg.jpg

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本文引用的文献

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The Effect of Nintedanib in Post-COVID-19 Lung Fibrosis: An Observational Study.尼达尼布在新冠后肺纤维化中的作用:一项观察性研究。
Crit Care Res Pract. 2022 Sep 26;2022:9972846. doi: 10.1155/2022/9972846. eCollection 2022.
2
Lung function and radiological findings 1 year after COVID-19: a prospective follow-up.新冠肺炎后 1 年的肺功能和影像学发现:一项前瞻性随访。
Respir Res. 2022 Sep 12;23(1):242. doi: 10.1186/s12931-022-02166-8.
3
Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity.
新型冠状病毒感染后间质性肺疾病患者的血清生物标志物及其与新冠后遗症的关联
Pathogens. 2024 Jul 31;13(8):641. doi: 10.3390/pathogens13080641.
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Cardiopulmonary Complications after Pulmonary Embolism in COVID-19.COVID-19 相关肺血栓栓塞后心肺并发症。
Int J Mol Sci. 2024 Jul 2;25(13):7270. doi: 10.3390/ijms25137270.
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Pulmonary Sequelae of COVID-19: Focus on Interstitial Lung Disease.新型冠状病毒肺炎的肺部后遗症:关注间质性肺疾病。
Cells. 2023 Sep 8;12(18):2238. doi: 10.3390/cells12182238.
了解新型冠状病毒肺炎后间质性肺疾病(ILD):一种新的纤维炎症性疾病实体。
Intensive Care Med. 2022 Dec;48(12):1803-1806. doi: 10.1007/s00134-022-06877-w. Epub 2022 Sep 8.
4
Follow-Up CT Patterns of Residual Lung Abnormalities in Severe COVID-19 Pneumonia Survivors: A Multicenter Retrospective Study.严重 COVID-19 肺炎幸存者肺部残留异常的 CT 随访模式:一项多中心回顾性研究。
Tomography. 2022 Apr 20;8(3):1184-1195. doi: 10.3390/tomography8030097.
5
Chest CT-based Assessment of 1-year Outcomes after Moderate COVID-19 Pneumonia.基于胸部 CT 的中度 COVID-19 肺炎 1 年后结局评估。
Radiology. 2022 Nov;305(2):479-485. doi: 10.1148/radiol.220019. Epub 2022 May 10.
6
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study.英国一项前瞻性观察研究:长新冠的临床特征及炎症特征分析及其与住院后 1 年康复的关系。
Lancet Respir Med. 2022 Aug;10(8):761-775. doi: 10.1016/S2213-2600(22)00127-8. Epub 2022 Apr 23.
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Respir Res. 2022 Mar 21;23(1):65. doi: 10.1186/s12931-022-01994-y.