von Ardenne M
Z Gesamte Inn Med. 1986 Feb 15;41(4):85-91.
The measurement of the O2 status of the human organism, the knowledge of factors which influence it and the using and development, respectively, of measures for its permanent improvement are of great importance for the prevention diagnosis, prophylaxis and therapy. The O2-intake in rest of the organism is regarded as absolute characteristic of the oxygen status. In investigations of the dynamics of the status it is in most cases sufficient to use the arteriovenous Hb-O2 saturation difference as relative distinctive mark, the representative determination of which from routine measurements of pO2 in rest is discussed. From such measurements the strong dynamics of the O2 status was found. Apart from the deterioration with growing age the deterioration by stressor influences of different kind, in hyposthenias and the minima in the 24-hour-cycle were established. Improvements were measured after perseverance training and after treatments with processes of the oxygen multistep therapy. After discussion of the three basic steps of this therapy the 36-h-O2-multistep process and the 15-min-O2-multistep rapid process are mentioned as standard variants which are to be used ambulatorily. The rapid process is entered more in detail and the practice of its performance as well as the results of measurements of the typical pO2 in rest before and after these processes are discussed. Surprising is the existence of the increase effected of the arterial pO2 in rest and of the decrease of the venous pO2 in rest for weeks, months up to years.(ABSTRACT TRUNCATED AT 250 WORDS)
测量人体组织的氧气状态、了解影响该状态的因素以及分别采用并开发持续改善该状态的措施,对于预防、诊断、预防措施及治疗都极为重要。机体静息时的氧气摄入量被视为氧气状态的绝对特征。在对该状态动态变化的研究中,在大多数情况下,使用动静脉血红蛋白 - 氧饱和度差值作为相对特征标记就足够了,文中讨论了如何从静息时的pO2常规测量中进行代表性测定。通过此类测量发现了氧气状态的强烈动态变化。除了随年龄增长而恶化外,还确定了不同类型应激源影响导致的恶化、体力衰弱时的恶化以及24小时周期中的最低点。在进行耐力训练后以及采用氧气多步疗法治疗后,测量到了改善情况。在讨论了该疗法的三个基本步骤后,提到了36小时氧气多步疗法和15分钟氧气多步快速疗法作为可门诊使用的标准变体。对快速疗法进行了更详细的阐述,并讨论了其实施方法以及这些疗法前后静息时典型pO2测量结果。令人惊讶的是,静息时动脉pO2增加以及静脉pO2降低的情况可持续数周、数月甚至数年。(摘要截取自250字)