Gross Sebastian, Amacher Simon A, Rochowski Anton, Reiser Stefan, Becker Christoph, Beck Katharina, Blatter René, Emsden Christian, Nkoulou Coralie, Sutter Raoul, Tisljar Kai, Pargger Hans, Marsch Stephan, Hunziker Sabina
Medical Communication and Psychosomatic Medicine, University Hospital Basel, Basel, Switzerland.
Department of Intensive Care, University Hospital Basel, Basel, Switzerland.
Resusc Plus. 2023 Apr 5;14:100383. doi: 10.1016/j.resplu.2023.100383. eCollection 2023 Jun.
To assess the do-not-resuscitate preferences of the general Swiss population and to identify predictors influencing decision-making.
A nationwide web-based survey was conducted in Switzerland on a representative sample of the adult population. The primary endpoint was the preference for a "Do Not Resuscitate" order (DNR Code Status) vs. cardiopulmonary resuscitation (CPR Code Status) in a clinical case vignette of an out-of-hospital cardiac arrest. Secondary endpoint were participants' own personal preferences for DNR.
1138 subjects participated in the web-based survey, 1044 were included in the final analysis. Preference for DNR code status was found in 40.5% ( = 423) in the case vignette and in 20.3% ( = 209) when making a personal decision for themselves. Independent predictors for DNR Code Status for the case vignette were: Personal preferences for their own DNR Code Status (adjusted OR 2.44, 95%CI 1.67 to 3.55; < 0.001), intubation following respiratory failure (adjusted OR 1.95, 95%CI 1.20 to 3.18; = 0.007), time-period after which resuscitation should not be attempted (adjusted OR 0.91, 95%CI 0.89 to 0.93); < 0.001), and estimated chance of survival in case of a cardiac arrest (adjusted OR per decile 0.91, 95%CI 0.84 to 0.99, = 0.02; which was overestimated by all participants.
Main predictors for a DNR Code Status were personal preferences and the overestimation of good neurological outcome after cardiac arrest. Overestimation of positive outcomes after cardiac arrest seems to influence patient opinion and should thus be addressed during code status discussions.
评估瑞士普通人群的不进行心肺复苏偏好,并确定影响决策的预测因素。
在瑞士对成年人口的代表性样本进行了一项基于网络的全国性调查。主要终点是在院外心脏骤停的临床病例 vignette 中对“不进行心肺复苏”医嘱(DNR 代码状态)与心肺复苏(CPR 代码状态)的偏好。次要终点是参与者个人对 DNR 的偏好。
1138 名受试者参与了基于网络的调查,1044 名被纳入最终分析。在病例 vignette 中,40.5%(n = 423)的人偏好 DNR 代码状态,而在为自己做出个人决定时,这一比例为 20.3%(n = 209)。病例 vignette 中 DNR 代码状态的独立预测因素为:个人对自身 DNR 代码状态的偏好(调整后的 OR 为 2.44,95%CI 为 1.67 至 3.55;P < 0.001)、呼吸衰竭后插管(调整后的 OR 为 1.95,95%CI 为 1.20 至 3.18;P = 0.007)、不应尝试复苏的时间段(调整后的 OR 为 0.91,95%CI 为 0.89 至 0.93;P < 0.001)以及心脏骤停时的估计存活机会(每十分位数调整后的 OR 为 0.91,95%CI 为 0.84 至 0.99,P = 0.02;所有参与者均高估了该机会)。
DNR 代码状态的主要预测因素是个人偏好以及对心脏骤停后良好神经学结果的高估。对心脏骤停后积极结果的高估似乎会影响患者的意见,因此在代码状态讨论中应予以解决。