Department of Urology, Anhui Province Key Laboratory of Genitourinary Diseases, The Institute of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, Anhui, China.
Department of Urology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Front Endocrinol (Lausanne). 2023 Mar 30;14:1135024. doi: 10.3389/fendo.2023.1135024. eCollection 2023.
Abnormal body mass index (BMI) is associated with an increased risk of erectile dysfunction (ED). However, the relationship between different BMI categories and the levels of ED severity remains unclear. In the current study, 878 men from the andrology clinic in Central China were recruited. Erectile function was assessed by the International Index of Erectile Function (IIEF) scores. Questionnaires included questions about demographic characteristics (age, height, weight, educational status), lifestyle habits (drinking, smoking, sleep time), and medical history. Logistic regression was used to examine the association between ED risk and BMI. The incidence of ED was 53.1%. BMI was significantly higher in men from the ED group than in those from the non-ED group ( = 0.01). Compared with the normal weight group, obese men had a higher risk of ED (OR = 1.97, 95% CI = 1.25-3.14, = 0.004), even after adjustment for potential confounders (OR = 1.78, 95% CI = 1.10-2.90, = 0.02). Moreover, the positive correlation between obesity and moderate/severe ED severity was confirmed by logistic regression analysis (moderate/severe ED, OR = 2.71, 95% CI = 1.44-5.04, = 0.002), even after adjusting for potential confounders (OR = 2.51 95% CI = 1.24-5.09, = 0.01). Collectively, our findings indicate a positive correlation between obesity and the risk of moderate/severe ED. Clinicians could pay more attention to moderate/severe ED patients to maintain a healthy body weight to improve erectile function.
异常的体重指数（BMI）与勃起功能障碍（ED）的风险增加有关。然而，不同 BMI 类别与 ED 严重程度之间的关系尚不清楚。在目前的研究中，从中原地区男科诊所招募了 878 名男性。勃起功能通过国际勃起功能指数（IIEF）评分进行评估。问卷包括人口统计学特征（年龄、身高、体重、教育程度）、生活方式习惯（饮酒、吸烟、睡眠时间）和病史。使用逻辑回归检查 ED 风险与 BMI 之间的关联。ED 的发病率为 53.1%。ED 组男性的 BMI 明显高于非 ED 组（ = 0.01）。与正常体重组相比，肥胖男性 ED 的风险更高（OR = 1.97，95%CI = 1.25-3.14， = 0.004），即使在调整了潜在混杂因素后（OR = 1.78，95%CI = 1.10-2.90， = 0.02）。此外，逻辑回归分析证实了肥胖与中重度 ED 严重程度之间的正相关关系（中重度 ED，OR = 2.71，95%CI = 1.44-5.04， = 0.002），即使在调整了潜在混杂因素后（OR = 2.51，95%CI = 1.24-5.09， = 0.01）。总的来说，我们的研究结果表明肥胖与中重度 ED 的风险呈正相关。临床医生可以更加关注中重度 ED 患者，以保持健康的体重，改善勃起功能。
