Laursen L C
Allergy. 1986 Feb;41(2):157-9. doi: 10.1111/j.1398-9995.1986.tb00292.x.
A new, simple technique for inhalation of aerosolized drugs is described: During the breathholding period after inhalation from a pressurized aerosol the patient lifts his right and lowers his left shoulder and vice versa to "disperse" the drug as well as possible in the lungs. Twenty outpatients suffering from reversible bronchial obstruction inhaled two puffs from a pressurized terbutaline aerosol in the morning on two consecutive days using the new inhalation technique on one day and their ordinary technique on the other in this randomised, cross-over trial. Compared with the conventional method the new inhalation technique significantly improved bronchodilation as measured by forced expiratory volume in 1st s and forced vital capacity during a period of 6 h. The new method of inhalation may improve treatment with aerosolized drugs.
本文描述了一种新的、简单的雾化药物吸入技术:在从加压气雾剂吸入后的屏气期间,患者抬起右肩并降低左肩,反之亦然,以便尽可能地将药物“分散”到肺部。在这项随机交叉试验中,20名患有可逆性支气管阻塞的门诊患者连续两天在早晨从加压特布他林气雾剂中吸入两喷,一天使用新的吸入技术,另一天使用他们常用的技术。与传统方法相比,新的吸入技术在6小时内通过第1秒用力呼气量和用力肺活量测量,显著改善了支气管扩张。这种新的吸入方法可能会改善雾化药物的治疗效果。