Abdelhakim Mohamed, Dohi Teruyuki, Ogawa Rei
Department of Plastic, Reconstructive, and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan.
Plast Reconstr Surg Glob Open. 2023 Apr 14;11(4):e4921. doi: 10.1097/GOX.0000000000004921. eCollection 2023 Apr.
Pathological scars (including keloids, hypertrophic scars, and scar contractures) are present with high severity among certain populations, particularly in Asians and Africans who are highly prone to develop scars. Understanding the patho-mechanism that underlies scarring, such as mechanosignaling, systemic, and genetic factors, as well as optimal surgical techniques and integrated noninvasive therapeutic methods can guide clinicians to develop treatment protocols that can overcome these issues. This report summarizes a congress at Pacifico Yokohama (Conference Center) on December 19, 2021 involving researchers and clinicians from diverse disciplines who convened to discuss current clinical, preclinical, and most recent research advances in understanding pathological scarring, keloid and hypertrophic scar management, and research progress in wound healing. Presenters described the advances in scar therapies, understanding scarring mechanisms, and scar prevention and assessments tools. Moreover, presenters addressed the challenges during the COVID-19 pandemic and using telemedicine in management of scar patients.
病理性瘢痕（包括瘢痕疙瘩、增生性瘢痕和瘢痕挛缩）在某些人群中严重程度较高，尤其是在极易形成瘢痕的亚洲人和非洲人中。了解瘢痕形成的病理机制，如机械信号传导、全身因素和遗传因素，以及最佳手术技术和综合非侵入性治疗方法，可以指导临床医生制定能够克服这些问题的治疗方案。本报告总结了2021年12月19日在横滨太平洋会展中心（会议中心）召开的一次大会，参会人员包括来自不同学科的研究人员和临床医生，他们齐聚一堂，讨论了病理性瘢痕、瘢痕疙瘩和增生性瘢痕管理方面当前的临床、临床前及最新研究进展，以及伤口愈合方面的研究进展。演讲者介绍了瘢痕治疗、瘢痕形成机制理解、瘢痕预防和评估工具方面的进展。此外，演讲者还探讨了新冠疫情期间的挑战以及在瘢痕患者管理中使用远程医疗的情况。
