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用于抗氧化、细胞活力及抗菌效果的绿色微波合成硒纳米球

Greener microwave synthesized Se nanospheres for antioxidant, cell viability, and antibacterial effect.

作者信息

Jeevanantham V, Tamilselvi D, Rathidevi K, Bavaji S R

机构信息

Department of Chemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Tiruchengode, Namakkal, Tamilnadu 637205 India.

Department of Chemistry, Rathinam Technical Campus, Coimbatore, Tamilnadu 641021 India.

出版信息

J Mater Res. 2023;38(7):1909-1918. doi: 10.1557/s43578-023-00965-3. Epub 2023 Mar 16.

Abstract

Selenium nanocrystals (SeNPs) were developed using fruit (CGF) extract by green microwave approach. The morphological characters revealed that the quasi SeNPs with dimensions ranging from 12 to 24 nm have been arranged in encapsulated spherical geometries with dimensions ranging from 0.47 to 0.71 m. The DPPH assay revealed that SeNPs at a concentration of 70 µl of 99.2% had the greatest possible scavenging capacity. The nanoparticle concentrations were around 500 g/mL and the cellular uptake of SeNPs through living thing extracellular matrix cell lines in vitro was limited to 75.1 ± 3.8%. The biocidal activity was tested against , , and strains. Since it had the greatest MIC against with 32 mm compared with the reference antibiotics. These incredible qualities of SeNPs suggest that attempting to manipulate multi-purpose nanoparticles for powerful and flexible wound and skin therapeutic innovations is very impressive.

摘要

通过绿色微波法利用水果(CGF)提取物制备了硒纳米晶体(SeNPs)。形态特征表明,尺寸范围为12至24纳米的准SeNPs排列成尺寸范围为0.47至0.71微米的封装球形结构。DPPH测定表明,浓度为70微升、99.2%的SeNPs具有最大的清除能力。纳米颗粒浓度约为500微克/毫升,体外通过生物细胞外基质细胞系对SeNPs的细胞摄取限制在75.1±3.8%。对 、 和 菌株测试了杀菌活性。由于与参考抗生素相比,它对 的最小抑菌浓度最大,为32毫米。SeNPs的这些惊人特性表明,尝试操纵多功能纳米颗粒用于强大而灵活的伤口和皮肤治疗创新是非常令人印象深刻的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3195/10019793/cae129c6001c/43578_2023_965_Fig1_HTML.jpg

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