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单油酸甘油酯、单亚油酸甘油酯和γ-亚麻醇对非洲猪瘟病毒的灭活及抑制作用。简要报告。

Inactivation and inhibition of African swine fever virus by monoolein, monolinolein, and gamma-linolenyl alcohol. Brief report.

作者信息

Sola A, Rodríguez S, García Gancedo A, Vilas P, Gil-Fernández C

出版信息

Arch Virol. 1986;88(3-4):285-92. doi: 10.1007/BF01310882.

DOI:10.1007/BF01310882
PMID:3707358
Abstract

Monoolein, monolinolein and (most strongly) gamma-linolenyl alcohol inactivate ASF virus and inhibit its replication in Vero cells at 25 micrograms/ml while at 10 micrograms/ml no inactivation occurs but inhibition of replication in tissue culture is observed. This suggests two possibly different action mechanisms.

摘要

单油酸甘油酯、单亚油酸甘油酯以及（效果最显著的）γ-亚麻醇在浓度为25微克/毫升时可使非洲猪瘟病毒失活，并抑制其在非洲绿猴肾细胞中的复制，而在浓度为10微克/毫升时虽不会使病毒失活，但可观察到对其在组织培养中的复制有抑制作用。这表明可能存在两种不同的作用机制。

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