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[淋巴肉芽肿组织学变异型的细胞学验证]

[Cytological verification of histological variants of lymphogranulomatosis].

作者信息

Lazarev I M

出版信息

Arkh Patol. 1986;48(2):19-23.

PMID:3707385
Abstract

Punch biopsies of the affected lymph nodes from 60 patients with lymphogranulomatosis were examined in order to verify cytologically the histological variants of the disease. It was established by a correlation between the cytological picture and histological diagnosis that the morphological structure of Berezovsky--Sternberg cells is the basis for the cytological verification of the lymphogranulomatosis histological type. Cells with polymorphic nuclei containing large nucleoli are characteristic of a mixed-cell variant of the tumour, So-called lacunar cells with a clear cytoplasm and multiple small monomorphic nuclei with small nucleoli are specific for a nodular variant. Pronounced cell polymorphism is characteristic of the so-called reticular type with suppression of lymphoid tissue; this type of lymphogranulomatosis is verified tentatively if an essential number of lymphoid cells are present in smears.

摘要

为了从细胞学角度验证淋巴肉芽肿病的组织学变体,对60例淋巴肉芽肿病患者受累淋巴结进行了打孔活检。通过细胞学图像与组织学诊断之间的相关性确定,贝利佐夫斯基-施特恩贝格细胞的形态结构是从细胞学角度验证淋巴肉芽肿病组织学类型的基础。具有多形核且含有大核仁的细胞是肿瘤混合细胞变体的特征,具有清晰细胞质和多个带有小核仁的小单形核的所谓陷窝细胞是结节变体所特有的。明显的细胞多形性是所谓网状型伴淋巴组织受抑制的特征;如果涂片中有大量淋巴细胞,则初步验证为这种类型的淋巴肉芽肿病。

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