Shcherbakova M G, Kolygin B A, Puchkov Iu G
Arkh Patol. 1978;40(9):29-38.
Examinations of punctates and impressions of lymph nodes from 68 children with primary untreated lymphogranulomatosis permitted to develop the criteria for differential cytological diagnosis of all types and variants of lymphogranulomatosis on the basis of histogenetic analysis and clinico-morphological comparisons, according to histological classification of the WHO. This proved to be possible only after it had been assumed that the original tumor cell must be a semi-stem cell of bone-marrow origin of histiocytic-reticular shoot which normally provides for physiological regeneration of reticular network of the lymph node. It appears that such a cell is a small lymphocyte-like cell with invaginated nucleus, the so-called small cleaved cell.
对68例未经治疗的原发性淋巴肉芽肿病患儿的淋巴结穿刺物和印片进行检查，依据世界卫生组织的组织学分类，通过组织发生学分析和临床形态学比较，得以制定出淋巴肉芽肿病所有类型和变体的鉴别细胞学诊断标准。只有在假定原始肿瘤细胞必定是组织细胞-网状细胞系骨髓来源的半干细胞（该细胞通常负责淋巴结网状网络的生理性再生）之后，才有可能做到这一点。看来这样的细胞是一种核内陷的小淋巴细胞样细胞，即所谓的小裂细胞。
