Tsodikova L B, Lushnikov E F
Arkh Patol. 1977;39(3):25-31.
Histological and cytological studies of preparations of peripheral lymphatic nodes in 1081 patients before treatment were carried out. In 76 patients there were also investigated morphological changes in the spleen, mesenteric lymphatic nodes and parts of the liver obtained in laparotomy. Basing on the analysis of the literature and their own findings, the authors think it reasonable to single out the following 8 histological variants of untreated lymphogranulomatosis: focal lesion; a group of variants with nodular sclerosis, with various cellular composition--lymphocytic predominance, mixed cellularity, predominance of lacunar cells; a group of variants without sclerosis consisting of lymphoid predominance and mixed cellular variant; a group of lymphatic depletion combining the reticular variant and diffuse fibrosis. The variants indicated above may be both independent and transitional stages.
对1081例患者治疗前外周淋巴结制剂进行了组织学和细胞学研究。其中76例患者还对剖腹术中获取的脾脏、肠系膜淋巴结和部分肝脏的形态变化进行了研究。基于文献分析和自身研究结果，作者认为将未经治疗的淋巴肉芽肿病的以下8种组织学变体区分出来是合理的：局灶性病变；一组具有结节性硬化的变体，具有不同的细胞组成——淋巴细胞为主、混合细胞性、陷窝细胞为主；一组无硬化的变体，包括淋巴细胞为主和混合细胞变体；一组淋巴耗竭变体，合并网状变体和弥漫性纤维化。上述变体可能既是独立阶段，也是过渡阶段。
