Pediatric Research Institute, Children's Hospital Affiliated to Shandong University, Ji'nan 250022, China; Shandong University of Traditional Chinese Medicine, Class of 2021, Doctoral Candidates, Ji'nan 250355, China; Tumor Minimally Invasive Comprehensive Treatment Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji'nan 250021, China.
Pediatric Research Institute, Children's Hospital Affiliated to Shandong University, Ji'nan 250022, China.
Stem Cell Res. 2023 Jun;69:103097. doi: 10.1016/j.scr.2023.103097. Epub 2023 Apr 15.
We used peripheral blood mononuclear cells (PBMCs) from a healthy 14-day-old boy donor to reprogram a pluripotent stem cells (iPSCs) line. The iPSCs line SDQLCHi049-A had a normal karyotype, pluripotent markers, and three-line differentiation potential. This cell line can be used as a control model for study on pathological mechanisms of diseases and drug development, particularly for study of childhood diseases.
我们使用来自一名健康 14 天大的男婴供体的外周血单核细胞（PBMCs）对多能干细胞（iPSCs）系进行重编程。该 iPSCs 系 SDQLCHi049-A 具有正常的核型、多能标志物和三系分化潜能。该细胞系可用作研究疾病病理机制和药物开发的对照模型，特别是用于研究儿童疾病。
