Ahmad Rozaziana, Azman Khairunnuur Fairuz, Yahaya Rosliza, Shafin Nazlahshaniza, Omar Norsuhana, Ahmad Asma Hayati, Zakaria Rahimah, Wijaya Adi, Othman Zahiruddin
School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.
Faculty of Medicine, Medical Campus, Universiti Sultan Zainal Abidin, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, Malaysia.
AIMS Neurosci. 2023 Mar 17;10(1):5-32. doi: 10.3934/Neuroscience.2023002. eCollection 2023.
This review aims to perform a bibliometric analysis of the research related to brain-derived neurotrophic factor (BDNF) in schizophrenia and offer suggestions for further work. Based on the keywords used, our study retrieved 335 documents for further analysis using a combination of three bibliometric techniques: co-word analysis, document co-citation analysis, and bibliographic coupling. A general rising trend in the number of publications was found in BDNF and schizophrenia research. Researchers from China and the United States have mostly researched BDNF and schizophrenia. Molecular Psychiatry is the most prestigious journal in the field of BDNF and schizophrenia research. The main topics and important research areas are cognition and the involvement of BDNF as a neurobiological marker (pathogenesis, therapy monitoring, and risk factors). Future research is anticipated to concentrate on relevant subjects, such as factors that affect BDNF levels or are connected to BDNF dysfunction in schizophrenia, as well as animal models of schizophrenia, in addition to cognition in schizophrenia.
本综述旨在对精神分裂症中与脑源性神经营养因子（BDNF）相关的研究进行文献计量分析，并为进一步的研究工作提供建议。基于所使用的关键词，我们的研究检索了335篇文献，使用共词分析、文献共被引分析和文献耦合这三种文献计量技术的组合进行进一步分析。BDNF与精神分裂症研究的出版物数量呈现出总体上升趋势。来自中国和美国的研究人员对BDNF和精神分裂症的研究最多。《分子精神病学》是BDNF和精神分裂症研究领域最具声望的期刊。主要主题和重要研究领域是认知以及BDNF作为神经生物学标志物的参与情况（发病机制、治疗监测和危险因素）。预计未来的研究将集中在相关主题上，例如影响BDNF水平或与精神分裂症中BDNF功能障碍相关的因素，以及精神分裂症的动物模型，此外还有精神分裂症中的认知。
